80870-36-6

Basic information

• Product Name: L-Leucine, N-(phenylmethylene)-, phenylmethyl ester
• CAS NO: 80870-36-6
• Molecular Formula: C20H23NO2
• Molecular Weight: 309.408
• Mol File: 80870-36-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Leucine, N-(phenylmethylene)-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, N-(phenylmethylene)-, phenylmethyl ester(80870-36-6)
• EPA Substance Registry System: L-Leucine, N-(phenylmethylene)-, phenylmethyl ester(80870-36-6)

Safety Data

• Hazardous Substances Data: 80870-36-6(Hazardous Substances Data)

Upstream product

• 1738-77-8 L-leucine benzyl ester p-toluenesulfonate 
• 100-52-7 benzaldehyde 

Downstream Products

• 80870-37-7 1-(1(S)-benzyloxycarbonyl-3-methylbutyl)-3(S)-azido-4(R)-phenylazetidin-2-one 
• 80924-56-7 1-(1(S)-benzyloxycarbonyl-3-methylbutyl)-3(R)-azido-4(S)-phenylazetidin-2-one 
• 81135-34-4 Boc-D-Ala-MeLeu-OBzl 
• 109745-83-7 (S)-2-[(3-Cyano-4,6-dimethyl-pyridin-2-ylsulfanyl)-methyl-amino]-4-methyl-pentanoic acid benzyl ester 
• 48168-99-6 N-methyl-L-leucine benzyl ester 

Relevant articles and documents

Amino Acids and Peptides, 63. - Peptide Synthesis via N- or O-Activation of Amino Acids with 1,2-Dihydro-4,6-dimethyl-2-thioxo-3-pyridinecarbonitrile. - Synthesis of the 8-11 Tetrapeptide Sequence of Cyclosporin

Peptides and N-methyl peptides have been prepared in high yields and nearly free of racemisation via N-activation (Scheme 1) or O-activation (Scheme 2) of N-acylamino acids and N-acyl-N-methylamino acids, respectively, by 1,2-dihydro-4,6-dimethyl-2-thioxo