808743-18-2

Upstream product

• 145823-43-4 diacetyl-4-amino-3-methylphenol 
• 7697-37-2 nitric acid 
• 108-24-7 acetic anhydride 
• 120-66-1 N-(2-methylphenyl)acetamide 
• 64-19-7 acetic acid 
• 39495-15-3 4-acetamido-3-methylphenol 
• 2835-99-6 4-amino-3-methylphenol 

Downstream Products

• 808743-24-0 N-(4-hydroxy-2-methyl-6-nitrophenyl)acetamide 
• 861086-22-8 acetic acid-(4-ethoxy-2-methyl-6-nitro-anilide) 
• 808743-87-5 ethyl 4-{4-[bis(tert-butoxycarbonyl)amino]-3-[(2,4-dichlorobenzyl)amino]-5-methylphenoxy}butanoate 
• 808743-89-7 ethyl 4-(3-[(2,4-dichlorobenzyl)amino]-5-methyl-4-{[(methylamino)carbonothioyl]amino}phenoxy)butanoate 
• 808743-85-3 ethyl 4-{4-[bis(tert-butoxycarbonyl)amino]-3-methyl-5-nitrophenoxy}butanoate 
• 808743-86-4 ethyl 4-{3-amino-4-[bis(tert-butoxycarbonyl)amino]-5-methylphenoxy}butanoate 
• 808743-88-6 ethyl 4-{4-amino-3-[(2,4-dichlorobenzyl)amino]-5-methylphenoxy}butanoate 
• 808743-66-0 ethyl 4-[3-methyl-5-nitro-4-(propionylamino)phenoxy]butanoate 
• 808743-25-1 ethyl 4-[4-(acetylamino)-3-methyl-5-nitrophenoxy]butanoate 
• 808743-26-2 ethyl 4-[4-(acetylamino)-3-amino-5-methylphenoxy]butanoate 
• 808743-59-1 ethyl 4-(4-amino-3-methyl-5-nitrophenoxy)butanoate 
• 808743-60-4 ethyl 4-(3,4-diamino-5-methylphenoxy)butanoate 
• 808743-58-0 4-(4-amino-3-methyl-5-nitrophenoxy)butanoic acid 

Relevant academic research and scientific papers

Acylamino-Directed Specific Sequential Difunctionalizations of Anilides via Metal-Free Relay Reactions for p-Oxygen and o-Nitrogen Incorporation

Novel acylamino-directed relay disubstitutions realize the sequential difunctionalizations of anilides (1) under mild and metal-free conditions for the first time. This [bis(trifluoroacetoxy)iodo]benzene (PIFA) and BF3·Et2O promoted straightforward reaction produces a series of p-acetoxyl- or p-alkoxyl-o-nitro-N-arylamides (2), which are key scaffolds of various drugs, functional materials, and bioactive molecules. The flexibility with respect to the functional groups in these products affords this novel protocol excellent versatility for synthetic applications.

Novel Compounds

The present invention relates to the new compounds of general formula I wherein A, U, V, X, Y, R1, R2 and R3 are defined as stated hereinafter, the tautomers, the isomers thereof, the diastereomers, the enantiomers, the hydrates, the mixtures and the salts thereof as well as the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, their use and processes for preparing them.

BENZIMIDAZOLE COMPOUNDS

The present invention provides novel benzimidazole compounds of the formula (I): wherein each symbol is as defined in the specification, salts thereof and prodrugs thereof, which are useful in treating, for example, the diseases curable through decrease in blood sugar level.