80922-27-6

Basic information

• Product Name: 5-Hydroxy-1,3,5-triphenyl-3-pyrrolin-2-on
• Synonyms: 5-Hydroxy-1,3,5-triphenyl-3-pyrrolin-2-on
• CAS NO: 80922-27-6
• Molecular Weight: 327.382
• Mol File: 80922-27-6.mol

Chemical Properties

• CAS DataBase Reference: 5-Hydroxy-1,3,5-triphenyl-3-pyrrolin-2-on(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hydroxy-1,3,5-triphenyl-3-pyrrolin-2-on(80922-27-6)
• EPA Substance Registry System: 5-Hydroxy-1,3,5-triphenyl-3-pyrrolin-2-on(80922-27-6)

Safety Data

• Hazardous Substances Data: 80922-27-6(Hazardous Substances Data)

Upstream product

• 1176777-73-3 C₂₂H₁₇NO₂ 
• 15811-37-7 1,2,4-triphenyl-1H-pyrrole 
• 762-04-9 phosphonic acid diethyl ester 
• 80922-16-3 Triphenyl(α-phenylcinnamyl)phosphoniumbromid 
• 34862-96-9 3-bromro-1,3-diphenyl-1-propene 
• 3412-44-0 1,3-diphenylpropene 
• 80922-45-8 ((Z)-1,3-Diphenyl-allylidene)-triphenyl-λ⁵-phosphane 
• 103-71-9 phenyl isocyanate 

Relevant articles and documents

Exploring tertiary enamides as versatile synthons in organic synthesis

Tertiary enamides have long been thought of as stable and marginally valuable enamine variants in synthesis. This notion has been challenged, however, in recent years. Enabling the regulation of the cross-conjugation system of the tertiary enamides has been successfully shown to enhance delocalization of the nitrogen lone-pair electrons into a carbon-carbon double, thereby reinvigorating the enaminic reactivity of the tertiary enamides. In this article, I summarize the recent advances in the exploration of the nucleophilic reactions of tertiary enamides and their applications in the synthesis of natural products and heterocyclic compounds of biological and pharmaceutical relevance, with a primary focus on our own work.

An expedient synthesis of pyrrole-2-phosphonates via direct oxidative phosphorylation and γ-hydroxy-γ-butyrolactams from pyrroles

An expedient oxidative phosphorylation of pyrroles has been disclosed. The reaction of dialkyl phosphite and pyrrole in the presence of AgNO 3/K2S2O8 in DMF/H2O (8:1) produced pyrrole-2-phosphonates in good yields. In the absence of dialkyl phosphite, γ-hydroxy-γ-butyrolactam derivative was formed as a major product.

Highly efficient and expedient synthesis of 5-hydroxy-1 H-pyrrol-2-(5 H)-ones from FeCl3-catalyzed tandem intramolecular enaminic addition of tertiary enamides to ketones and 1,3-hydroxy rearrangement

Catalyzed by FeCl3 under very mild conditions, tertiary enamides underwent a highly efficient intramolecular enaminic addition reaction to the ketonic carbonyls followed by 1,3-hydroxy rearrangement to produce 5-hydroxy-1H-pyrrol-2(5H)-ones in

Reactions of Allylidenephosphoranes with Heterocumulenes,I. - Vinylketenimines

According to their α-substituent the allylidenephosphoranes 4 are converted by isocyanates either via Wittig reaction into the hitherto little known vinylketenimines 7 or by carbamoylation and ring closure into the pyrrolone 5 or the 3-pyridylidenephospho