15811-37-7

Usage

Type of compound

Heterocyclic aromatic organic compound

Structure

Pyrrole ring with three phenyl groups attached at the 1, 2, and 4 positions

Type of pyrrole

1,2,4-triphenyl-1H-pyrrole

Potential applications

Organic electronic devices, building block for the synthesis of new materials

Field of interest

Organic chemistry and materials science

Notable features

Unique structure, interesting chemical and physical properties

Upstream product

• 860760-14-1 2-chloro-1,3,5-triphenyl-pyrrole 
• 10034-85-2 hydrogen iodide 
• 7462-71-7 (2Z)-4-bromo-1,3-diphenylbut-2-en-1-one 
• 62-53-3 aniline 
• 495-45-4 dypnone 
• 100-52-7 benzaldehyde 
• 67-56-1 methanol 
• 69814-23-9 4-oxo-2,4-diphenylbutanal 
• 6277-67-4 4-nitro-1,3-diphenyl-butan-1-one 
• 40088-97-9 (1,3-diphenyl-but-3-enylidene)-phenyl-amine 
• 122-78-1 phenylacetaldehyde 
• 622-37-7 Phenyl azide 
• 115872-74-7 2,4-Diphenyl crotonaldehyde 
• 23147-58-2 glycolaldehyde dimer 

Downstream Products

• 1526987-34-7 C₂₆H₂₆NO₃P 
• 80922-27-6 5-Hydroxy-1,3,5-triphenyl-3-pyrrolin-2-on 
• 83049-40-5 1,3,5-Triphenyl-2-benzoyl-4-nitropyrrole 
• 83049-39-2 1,3,5-Triphenyl-2-benzoyl-4-acetylpyrrole 
• 83049-38-1 1,3,5-Triphenyl-2-benzoyl-4-bromopyrrole 
• 76671-72-2 1-Phenyl-2-benzoyl-3,5-diphenylpyrrole 

Relevant academic research and scientific papers

Synthesis of N-aryl-substituted pyrroles via γ-bromodypnone

A series of 1-aryl-2,4-diphenylpyrroles were obtained by the reaction of 4-bromo-1,3-diphenyl-2-buten-1-one (γ-bromodypnone) with substituted anilines in the presence of sodium acetate. In the reaction with di-and trimethylenediamines the corresponding 1,

1,2,4-Triphenylpyrroles: Synthesis, Structure and Luminescence Properties

Pyrroles are widely found in natural products and play an important role in biological processes. Certain pyrrole derivatives are fluorescent and may be used as molecular probes or biomarkers in the diagnosis of diseases, such as Alzheimer's or Parkinson'

Pd-catalyzed imine-directed intramolecular C–N bond formation through C(sp3)–H activation: An efficient approach to multisubstituted pyrroles

An atom-economic approach to synthesize 1,2,4-trisubstituted pyrroles through palladium-catalyzed imine-directed intramolecular C(sp3)–H amination reaction has been developed. The imine group acts as a directing group as well as an intramolecular nucleophile for the first time in intramolecular C–N bonds formation reactions.

Visible-Light-Driven Synthesis of 1,3,4-Trisubstituted Pyrroles from Aryl Azides

The synthesis of 1,3,4-trisubstituted pyrroles via visible-light mediated photoredox catalyzed condensation of arylazides and aldehydes has been reported herein. The methodology avoids the use of stoichiometric oxidants and provides the corresponding N-co

Synthesis of Multisubstituted Pyrroles from Enolizable Aldehydes and Primary Amines Promoted by Iodine

1,2,4-Trisubstituted pyrroles were synthesized from enolizable aliphatic aldehydes and primary aliphatic amines by using iodine as the dual Lewis acid/mild oxidant. In the presence of 3.0 equiv of TBHP, enolizable α,β-unsaturated aldehyde, for example, co

α-Unsubstituted Pyrroles by NHC-Catalyzed Three-Component Coupling: Direct Synthesis of a Versatile Atorvastatin Derivative

A practical one-pot cascade reaction protocol provides direct access to valuable 1,2,4-trisubstituted pyrroles. The process involves an N-heterocyclic carbene (NHC)-catalyzed Stetter-type hydroformylation using glycolaldehyde dimer as a novel C1 building-block, followed by a Paal-Knorr condensation with primary amines. The reaction makes use of simple and commercially available starting-materials and catalyst, an important feature regarding applicability and utility. Low catalyst loading under mild reaction conditions afforded a variety of 1,2,4-substituted pyrroles in a transition-metal-free reaction with high step economy and good yields. This methodology is applied in the synthesis of a versatile Atorvastatin precursor, in which a variety of modifications at the pyrrole core structure are possible.

MANUFACTURING METHOD OF DIPYRRYL KETONES AND DIPYRRYL KETONES MADE BY THE SAME

The present invention relates to a manufacturing method of a dipyrryl ketone and dipyrryl ketone manufactured by the method wherein the manufacturing method of dipyrryl ketone is allowed to manufacture dipyrryl ketone from 2-carboxylic acid pyrrole compounds in a high yield with use of a simple process.COPYRIGHT KIPO 2015

Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade

A gold-catalyzed cascade hydroamination/cyclization reaction of α-amino ketones with alkynes to form substituted pyrroles has been developed. The method offers several advantages such as high regioselectivity with the tested cases, wide functional group tolerance, and easily accessible starting materials. The synthetic utility of the obtained pyrrole products was demonstrated by their efficient transformations to 2-vinylated pyrroles via gold-catalyzed intermolecular hydroarylation.

Pd-catalyzed carbonylative cycloamidation of ketoimines for the synthesis of pyrido[1,2-a]pyrimidin-4-ones

The Pd(ii)-catalyzed pyridine-directed carbonylative cycloamidation of ketoimines has provided an efficient protocol for assembly of pyrido[1,2-a]pyrimidin-4-ones. This journal is

Synthesis of 2,2′-dipyrryl ketones from pyrrole-2-carboxylic acids with trifluoroacetic anhydride

An efficient synthesis of 2,2′-dipyrryl ketones has been carried out from pyrrole-2-carboxylic acids using trifluoroacetic anhydride (TFAA). Simultaneous generation of both mixed anhydride and 2-unsubstituted pyrrole, via facile decarboxylation with in-si