809231-36-5

Upstream product

• 110-62-3 pentanal 
• 809231-35-4 8-benzyloxy-2-bromo-3-[(2E)-4-(t-butyldimethylsiloxy)-2-butenyl]-1,5,6-trimethoxynaphthalene 
• 693784-40-6 4-acetoxy-5-benzyloxy-7,8-dimethoxy-naphthalene-2-carboxylic acid ethyl ester 
• 693784-43-9 2-(5-benzyloxy-3-bromo-4,7,8-trimethoxy-naphthalen-2-yl)-oxirane 
• 693784-36-0 8-benzyloxy-2-bromo-3-hydroxymethyl-5,6-dimethoxy-naphthalen-1-ol 
• 828940-38-1 5-benzyloxy-4-hydroxy-7,8-dimethoxy-naphthalene-2-carboxylic acid ethyl ester 
• 693784-37-1 5-benzyloxy-3-bromo-4-hydroxy-7,8-dimethoxy-naphthalene-2-carbaldehyde 
• 693784-42-8 5-benzyloxy-3-bromo-4,7,8-trimethoxynaphthalene-2-carbaldehyde 
• 693784-41-7 8-benzyloxy-3-hydroxymethyl-5,6-dimethoxy-1-naphthol 
• 809231-33-2 ethyl (2E)-4-(5-benzyloxy-3-bromo-4,7,8-trimethoxy-2-naphthyl)but-2-enoate 
• 809231-34-3 (2E)-4-(5-benzyloxy-3-bromo-4,7,8-trimethoxy-2-naphthyl)but-2-en-1-ol 

Downstream Products

• 828940-62-1 Acetic acid (E)-4-[5-benzyloxy-3-(1-hydroxy-pentyl)-4,7,8-trimethoxy-naphthalen-2-yl]-but-2-enyl ester 

Relevant academic research and scientific papers

Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity

The synthesis naphthoquinones exhibited stronger activity than the pyranonaphthoquinone-type compound having moderate inhibitory activity against Cdc25A protein phosphatase. The novel naphthalene-type analogues 14 and 18 and the naphthoquinone-type analog

The synthesis and biological activity of pyranonaphthoquione derivatives from Streptomyces sp. and their related substances

The total synthesis of a novel pyranonaphthoquinone (2) having Cdc25A phosphatase inhibitory activity is achieved. The key step in this synthetic pathway is the intramolecular Michael addition for construction of the pyran ring system. The inhibitory acti