828940-38-1Relevant articles and documents
The synthesis and biological activity of pyranonaphthoquione derivatives from Streptomyces sp. and their related substances
Shimbashi, Akiko,Tsuchiya, Ayako,Imoto, Masaya,Nishiyama, Shigeru
, p. 1925 - 1930 (2007/10/03)
The total synthesis of a novel pyranonaphthoquinone (2) having Cdc25A phosphatase inhibitory activity is achieved. The key step in this synthetic pathway is the intramolecular Michael addition for construction of the pyran ring system. The inhibitory acti