80953-49-7Relevant academic research and scientific papers
Dynamic Kinetic Resolution of Phosphinic Acid Derivatives via Nucleophilic Substitution at Phosphorus Center
Strzelecka, Dorota,Baok, Olga,Borowski, Piotr,Stankevi?, Marek
, p. 4922 - 4932 (2018/12/14)
Reaction of racemic phosphinic acid derivatives with chiral alcohols proceeds with predominant formation of one diastereomer. The highest level of enrichment has been obtained for transesterfication of racemic methyl benzylphenylphosphinate (64% de). The
Directed ortho-lithiation of unprotected diphenylphosphinic acids
Ya?ez Rodríguez, Víctor,Del águila, Miguel ángel,Iglesias, María José,López Ortiz, Fernando
scheme or table, p. 7355 - 7362 (2012/09/22)
Directed ortho lithiation of diphenylphosphinic acid and subsequent electrophilic trapping provides mono ortho-functionalized derivatives including enantiopure γ-aminophosphinic acids in moderate yields. Copper catalyzed coupling of the ortho anion leads to biphenyl-2,2′- diylbis(phenylphosphinic acid), a phosphorus analogue of biphenyl-2,2′- dicarboxylic acid. Preliminary studies of the metal-binding abilities of this O,O-chelating ligand towards a series of metal cations are included.
Synthesis of a novel diarylphosphinic acid: A distorted ground state mimic and transition state analogue for amide hydrolysis
Schuman, Marc,Lopez, Xabier,Karplus, Martin,Gouverneur, Véronique
, p. 10299 - 10307 (2007/10/03)
We describe herein the synthesis of a new unsymmetrical diarylphosphinic acid, a hapten aimed to produce catalytic antibodies for the hydrolysis of heterocyclic amides. The phosphinate functionality was selected as a mimic both of the tetrahedral intermed
