80960-09-4

Upstream product

• 5680-79-5 glycine ethyl ester hydrochloride 
• 504-02-9 1,3-cylohexanedione 
• 56-40-6 glycine 

Downstream Products

• 80960-19-6 Toluene-4-sulfonate[2-(carboxymethyl-amino)-6-oxo-cyclohex-1-enyl]-phenyl-iodonium; 
• 36646-77-2 3-(4-methoxyphenylamino)cyclohex-2-en-1-one 
• 1158819-63-6 methyl 2-((3-oxocyclohex-1-en-1-yl)amino)acetate 
• 1393726-42-5 2-(3-(3-bromophenylamino)-4,5,6,7-tetrahydro-2-(4-methoxyphenyl)-4-oxoindol-1-yl)acetic acid 
• 1393726-41-4 2-(3-(4-fluorophenylamino)-4,5,6,7-tetrahydro-2-(4-methoxyphenyl)-4-oxoindol-1-yl)acetic acid 
• 1393726-40-3 2-(3-(p-tolylamino)-4,5,6,7-tetrahydro-2-(4-methoxyphenyl)-4-oxoindol-1-yl)acetic acid 
• 1393726-39-0 2-(3-(4-bromophenylamino)-4,5,6,7-tetrahydro-2-(4-methoxyphenyl)-4-oxoindol-1-yl)acetic acid 
• 1393726-38-9 2-(3-(4-chlorophenylamino)-4,5,6,7-tetrahydro-2-(4-methoxyphenyl)-4-oxoindol-1-yl)acetic acid 
• 1393726-37-8 2-(3-(4-fluorophenylamino)-4,5,6,7-tetrahydro-4-oxo-2-p-tolylindol-1-yl)acetic acid 
• 1393726-36-7 2-(3-(4-chlorophenylamino)-4,5,6,7-tetrahydro-4-oxo-2-p-tolylindol-1-yl)acetic acid 

Relevant academic research and scientific papers

Unexpected dihydropyridinium derivatives using a multicomponent reaction containing unprotected amino acids

In this study, a multicomponent reaction (MCR) of amino acids, aldehydes, β-dicarbonyl compounds, and malononitrile is presented to obtain a novel class of dihydropyridinium scaffolds which are incorporating amino acid moieties. Some derivatives were obtained in tetrahydropyrido[2,3-d]pyrimidin form. The reaction proceeded through formation of a stable enolate as triethylammoniumenolate salt, which is isolable from the reaction mixture. The DFT calculations also confirm the stability of the formed dihydropyridinium structure. The docking studies of the synthesized compounds on the acetylcholinesterase target (PDB ID = 5FUM) show high potential inhibitory activities of these compounds in Alzheimer's disease.

IMINO COMPOUNDS AS PROTECTING AGENTS AGAINST ULTRAVIOLET RADIATIONS

The present invention relates to compounds having the general Formula I: which absorb UV radiations and protect biological materials as well as non-biological materials from damaging exposure to UV radiations. The present invention also relates to formulations and compositions comprising such compounds for use in absorbing UV radiations and in protecting biological materials as well as non-biological materials against UV radiations.