80962-03-4Relevant academic research and scientific papers
Preparation of acetals from aldehydes and alcohols under basic conditions
Grabowski, Jakub,Granda, Jaros?aw M.,Jurczak, Janusz
, p. 3114 - 3120 (2018/05/17)
A new, simple protocol for the synthesis of acetals under basic conditions from non-enolizable aldehydes and alcohols has been reported. Such reactivity is facilitated by a sodium alkoxide along with a corresponding trifluoroacetate ester, utilizing formation of sodium trifluoroacetate as a driving force for acetal formation. The usefulness of this protocol is demonstrated by its orthogonality with various acid-sensitive protecting groups and by good compatibility with functional groups, delivering synthetically useful acetals complementarily to the synthesis under acidic conditions from aldehydes and alcohols.
Synthesis, antibacterial and antifungal activities of some new azo anils containing pyrazole moiety
Sharma,Kaur, Jasvir,Kaur, Sandeep,Sharma, Poonam
, p. 227 - 237 (2014/03/21)
A series of azo compounds namely 3-(Phenylazo) benzaldehyde 1a-f, 3-(4-Nitrophenylazo) benzaldehyde 3a-f and 3- (1,5-Dimethyl-3-oxo-2-phenyl-2,3- dihydro-1H-pyrazol-4-yl-azo) benzaldehyde 6 were synthesized and then azo anils viz. 3-(Phenylazo)-1,5 dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H pyrazol-4-yl imino methyl benzene 2a-f, 4a-f and 7-9 have been synthesized from azo compounds by reacting with corresponding amines. All the compounds synthesized by conventional method are also prepared by using microwave irradiation method and are characterized by spectroscopic techniques (UV, FTIR and 1H NMR). The synthesized compounds have been screened for antimicrobial activity against bacteria viz. Mesorhizobium sp., Bacillus sp. and Pseudomonas sp., fungus (Ascochyta blight) and yeast (Sacchromycis cerevisiae). The azo anils show minor to moderate activity against bacteria and no activity against fungus and yeast. The activity shown by some compounds is due to substitution of chloro, methoxy or nitro group on phenyl ring or due to some heterocyclic moiety.
Oligo switches: Photoresponsive oligonucleotide conjugates by solid-supported click chemistry
Freeman, Colin,Vyle, Joseph S.,Heaney, Frances
, p. 1652 - 1655 (2013/03/14)
Photoresponsive oligonucleotides (ONs) incorporating isoxazole-linked azobenzene (AB) moieties were prepared by resin-supported nitrile oxide-alkyne cycloaddition (NOAC) chemistry. The thermal and photochromic properties of the modified ONs were significa
