80993-22-2Relevant academic research and scientific papers
An ammonia equivalent for the dimethyltitanocene-catalyzed intermolecular hydroamination of alkynes
Haak, Edgar,Siebeneicher, Holger,Doye, Sven
, p. 1935 - 1937 (2007/10/03)
(Equation presented) Commercially available α-aminodiphenylmethane 1 (benzhydrylamine) serves as a convenient ammonia equivalent in the dimethyltitanocene-catalyzed intermolecular hydroamination of alkynes. The primary formed imines can be hydrogenated and cleaved directly to the corresponding primary amines by catalytic hydrogenation using Pd/C as catalyst.
The synthesis of 1-aminobenzylphosphonic acids from benzylidenediphenylmethylamines, for use as structural units in antithrombotic tripeptides
Green, Donovan,Patel, Geeta,Elgendy, Said,Baban, Jehan A.,Claeson, Goran,Kakkar, Vijay V.,Deadman, John
, p. 5099 - 5108 (2007/10/02)
Acid hydrolyses of O,O-dimethyl or O,O-diethyl 1-(diphenylmethylamino) benzylphosphonate intermediates 2, formed from the addition at elevated temperature of dimethyl or diethyl phosphite to benzylidenediphenylmethylamines 1, generates 1-aminobenzylphosphonic acids 3 in good yield.
Synthesis of 1-Aminoalkane Phosphonic Acids via Benzhydrylic Schiff Bases
Issleib, Kurt,Doepfer, Klaus-Peter,Balszuweit, Arno
, p. 1392 - 1394 (2007/10/02)
A simple synthesis of 1-aminoalkanephosphonic acids is described.The addition of diethylphosphite to alkylidene- and arylidenebenzhydrylamines yields the N-benzhydryl-1-aminoalkanephosphonic acid esters.The title compounds are formed by treatment of the N-blocked esters with hydrobromic acid.The starting amine can be recycled from the hydrylbromide. - Key words: 1-Aminoalkane Phosphonic Acids, Benzhydrylic, Schiff Bases
