81015-98-7Relevant academic research and scientific papers
Cu-catalyzed asymmetric borylative cyclization of cyclohexadienone- containing 1,6-enynes
Liu, Ping,Fukui, Yuki,Tian, Ping,He, Zhi-Tao,Sun, Cai-Yun,Wu, Nuo-Yi,Lin, Guo-Qiang
supporting information, p. 11700 - 11703 (2013/09/02)
The first Cu-catalyzed asymmetric borylative cyclization of cyclohexadienone-containing 1,6-enynes is achieved through a tandem process: selective β-borylation of propargylic ether and subsequent conjugate addition to cyclohexadienone. The reaction proceeds with excellent regioselectivity and enantioselectivity to afford an optically pure cis-hydrobenzofuran framework bearing alkenylboronate and enone substructures. Furthermore, the resulting bicyclic products could be converted to bridged and tricyclic ring structures. This method extends the realm of Cu-catalyzed asymmetric tandem reactions using bis(pinacolato)diboron (B2pin 2).
THE SYNTHESIS OF QUINONE METHIDES FROM p-QUINOL BENZOATES
Guildford, Allen J.,Turner, Ralph W.
, p. 4835 - 4838 (2007/10/02)
A simple route to the quinone methides (1,R=Ar,R1=CO2Me) is described.
