35357-34-7Relevant articles and documents
Total synthesis of (±)-antroquinonol D
Sulake, Rohidas S.,Jiang, Yan-Feng,Lin, Hsiao-Han,Chen, Chinpiao
, p. 10820 - 10828 (2014)
Total synthesis of (±)-antroquinonol D, which is isolated from very expensive and rarely found Antrodia camphorata and which has potential anticancer properties, was achieved from 4-methoxyphenol. In addition, a Michael addition to dimethoxy cyclohexadien
Catalytic Enantioselective Diels-Alder Reactions of 1,4-Quinone Monoketals
Breuning, Matthias,Corey
, p. 1559 - 1562 (2001)
matrix presented Achiral 1,4-quinone monoketals function well as dienophiles in enantioselective Diels-Alder reactions catalyzed by a chiral Ti(IV) Lewis acid.
Thermal and Photochemical Rearrangements of Cyclopropyl Ethers of p-Quinols. Competing Reaction Pathways Leading to Five- and Six-Membered Ring Spirocyclic Ketones
Biggs, Timothy N.,Swenton, John S.
, p. 5568 - 5573 (1992)
Cyclopropyl ethers of p-quinols were prepared by reaction of 3''-methylenedispirocyclohexadiene-4',1''(3''H)-isobenzofuran> and the associated ketone with ethyl diazoacetate/rhodium(II) acetate and diethylzinc/methylene iodide, re
Ring-fused compound, pharmaceutical composition containing same and application of compound
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Paragraph 0287-0289, (2018/04/01)
The invention discloses a ring-fused compound, a preparation method thereof, pharmaceutical composition containing the compound and an application of the compound. A polycyclic compound (I) as well asan isomer, a prodrug, a stable isotopic derivative or pharmacologically acceptable salt of the compound (I) has the following structure. The polycyclic compound has good IDO1 and/or TDO2 inhibition functions, can effectively treat, relieve and/or prevent various diseases which are related with IDO1 and/or TDO2, such as cancer, virus infection, autoimmune diseases or the like.
Synthesis of o-chlorophenols via an unexpected nucleophilic chlorination of quinone monoketals mediated by N,N′-dimethylhydrazine dihydrochloride
Yin, Zhiwei,Zhang, Jinzhu,Wu, Jing,Green, Riana,Li, Sihan,Zheng, Shengping
supporting information, p. 2854 - 2858 (2014/05/06)
An unexpected nucleophilic chlorination of a quinone monoketal while carrying out a pyrazolidine synthesis has led to a general preparation of multisubstituted phenols. The products are obtained in good to high yields under mild conditions. The bridged pyrazolidines that were the original targets are obtained in the presence of a protic solvent. This journal is the Partner Organisations 2014.
Total synthesis and structural confirmation of (±)-cuevaene A
Craven, Philip G.E.,Taylor, Richard J.K.
supporting information, p. 5422 - 5425 (2012/10/30)
The total synthesis and structural reassignment of cuevaene A have been completed. The key synthetic steps in the total synthesis included a base-promoted double conjugate addition and further elaboration to generate the tricyclic core structure, followed by construction of the trienoic acid side chain. Detailed comparison of proton and carbon NMR data with published values enabled the connectivity of the natural product, which had been debated in earlier publications, to be confirmed.
A total synthesis of millingtonine a
Wegner, Jens,Ley, Steven V.,Kirschning, Andreas,Hansen, Anne-Lene,Montenegro Garcia, Javier,Baxendale, Ian R.
supporting information; experimental part, p. 696 - 699 (2012/04/17)
A total synthesis of millingtonine A, a diglycosylated alkaloid, has been accomplished. Millingtonine A possesses a unique racemic tricyclic core structure not known from any other natural or synthetic source until now. The synthesis features a key bond-f
Method for the Production of Substituted and Unsubstituted Cyclohexanone Monoketals
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Page/Page column 4, (2010/09/05)
The invention relates to a novel process for preparing and isolating known substituted and unsubstituted 1,4-cyclohexanone monoketals.
An efficient protocol for the enantioselective preparation of a key polyfunctionalized cyclohexane. New access to (R)- and (S)-4-hydroxy-2- cyclohexenone and (R)- and (S)-trans-cyclohex-2-ene-1,4-diol
Bayon, Pau,Marjanet, Georgina,Toribio, Gladis,Alibes, Ramon,De March, Pere,Figueredo, Marta,Font, Josep
, p. 3486 - 3491 (2008/09/21)
(Chemical Equation Presented) Starting from very accessible raw materials such as p-methoxyphenol, ethylene glycol, and thiophenol, a protocol has been developed to prepare multigram quantities of the polyfunctionalized cyclohexane (±)-7. A highly efficie
Synthesis of both enantiomers of conduritol C tetraacetate and of meso-conduritol D tetraacetate by oxidation of benzoquinone bis(ethylene acetal)
Lang, Martin,Ziegler, Thomas
, p. 768 - 776 (2008/02/07)
Epoxidation of p-benzoquinone bis(ethylene acetal) (1) with m-chloroperbenzoic acid or hydrogen peroxide/benzonitrile afforded corresponding monoepoxide 2, which was converted into p-benzoquinone mono(ethylene acetal) monoepoxide 5 with perchloric acid. D