81016-32-2

Upstream product

• 41467-26-9 1-(4-chlorophenyl)-3,3-bis(methylsulfanyl)-2-propen-1-one 
• 62-53-3 aniline 
• 99-91-2 para-chloroacetophenone 
• 103-72-0 phenyl isothiocyanate 
• 74-88-4 methyl iodide 

Downstream Products

• 120621-56-9 N-[5-(4-Chloro-benzoyl)-3-phenyl-3H-[1,2,3]triazol-4-yl]-4-methyl-benzenesulfonamide 
• 81016-12-8 (4-Chloro-phenyl)-(6-methylsulfanyl-1,2-diphenyl-4-thioxo-1,4-dihydro-pyrimidin-5-yl)-methanone 
• 81376-33-2 6-(4-Chloro-phenyl)-2-oxo-4-phenylamino-1,2-dihydro-pyridine-3-carbonitrile 
• 81376-45-6 6-(4-Chloro-phenyl)-1-methyl-2-oxo-4-phenylamino-1,2-dihydro-pyridine-3-carbonitrile 
• 116991-74-3 1-(4-Chloro-phenyl)-2-(1-phenyl-1H-tetrazol-5-yl)-ethanone 
• 120621-68-3 (5-Amino-1-phenyl-1H-[1,2,3]triazol-4-yl)-(4-chloro-phenyl)-methanone 
• 120621-75-2 (4-Chloro-phenyl)-(5-phenylamino-1H-[1,2,3]triazol-4-yl)-methanone 
• 116538-42-2 5-(4-Chloro-benzoyl)-4-hydroxy-6-methylsulfanyl-1-phenyl-1H-pyridin-2-one 
• 101476-61-3 3-anilino-5-p-chlorophenylpyrazole 

Relevant academic research and scientific papers

Synthesis of Novel Fluorinated Multisubstituted Pyrimidines and 1,5-Benzodiazepines via Fluorinated N,S-Acetals

An efficient and novel approach using highly versatile but less exploited monofluorinated α-oxoketene N,S-acetals as synthons for the synthesis of novel fluorinated multisubstituted pyrimidines and 1,5-benzodiazepines by cyclization with guanidine nitrate

In-Water Synthesis of 5-Thiolated 1,2,3-Triazoles from β-Thioenaminones by Diazo Transfer Reaction

The synthesis of 1,2,3-triazoles with a sulfur-based side chain has been accessed with the metal-free annulation reactions of readily available β-thiolated enaminones and tosyl hydrazine. By these reactions with water as the only medium, a broad array of

A Highly Efficient Approach for the Synthesis of Novel Trifluoroacetylated Enaminones using DBU as a Base

An efficient methodology has been developed for the synthesis of a variety of novel trifluoroacetylated enaminones by using trifluoroacetic anhydride in DCE as solvent and DBU as a base via electrophilic trifluoroacetylation. X-ray crystallographic studie

Copper-mediated intramolecular oxidative C-H/C-H cross-coupling of α-oxo ketene N, S -acetals for indole synthesis

CuCl2-mediated intramolecular C-H/C-H cross-dehydrogenative coupling (CDC) of thioalkyl-substituted α-acetyl or α-aroyl ketene N,S-acetals afforded 2-thioalkyl indoles. Tunable C-S bond transformations of the resultant indoles led to highly fun

Reaction of lithioamino anions with α-oxoketene dithioketals: An improved and a new general method for the synthesis of α-oxoketene S,N- and N,N-ketals

A new method has been developed for the preparation of α-oxoketene S,N- (A) and N,N-(B) ketals starting from α-oxoketene dithioketals by employing mild conditions. Thus, lithioamino anions 2a-c, 4 and 6 are treated with α-oxoketene dithioketals 1 to affor

Reaction of α-oxoketene dithioacetals with arylamines in the presence of BF3-OEt2 for the synthesis of ketene S,N-acetals

Reaction of α-oxoketene dithioacetals with arylamines was accelerated with a catalytic amount of BF3-OEt2 to give the corresponding α-oxoketene S,N-acetals selectively in good yields.