81044-13-5Relevant articles and documents
Occurrence of Even Telesubstitution in the Amination of Halogeno-2,6-naphthyridines
Haak, Henk J. W. van den,Plas, Henk C. van der
, p. 1673 - 1677 (1982)
The conversion of 1-halogeno-2,6-naphthyridines into 1-amino-2,6-naphthyridine is shown to proceed via an even telesubstitution process N(AE)tele process>.The amination of 2-bromo-1,5-naphthyridine into 2-amino-1,5-naphthyridine is shown to proceed via an SN(AE)ipso substitution mechanism.