81054-20-8Relevant academic research and scientific papers
Use of methylene chloride as a C1 unit in N,N-dialkylaminomethylation reaction
Souquet,Martens,Fleury
, p. 817 - 828 (2007/10/02)
Mannich products have been isolated in good yields with methylene chloride as a C1 unit, instead of formaldehyde. It is evidenced that, contrary to previous understanding, a high pressure procedure is not necessary required and that the methylene bisamines function as intermediates.
Amino- and Amidomethylation of N,N-Dimethylaniline and Related Derivatives
Boehme, Horst,Bomke, Ulrich,Denis, Jean-Pierre
, p. 40 - 47 (2007/10/02)
The reaction of N,N-dimethylaniline (4) with N-methylenemorpholinium chloride (10g) affords 2,4-bis(morpholinomethyl)-N,N-dimethylaniline (11g) via 4-(morpholinomethyl)-N,N-dimethylaniline (9g) as an intermediate.From 4-(dimethylaminomethyl)- or 4-(pyrrol
