810675-87-7Relevant academic research and scientific papers
Highly stereoselective Grignard addition to cis-substituted C-cyclopropylaldonitrones. The bisected s-trans transition state can be stabilized effectively by the Lewis acid-coordination
Kazuta, Yuji,Abe, Hiroshi,Matsuda, Akira,Shuto, Satoshi
, p. 9143 - 9150 (2007/10/03)
We previously found that Grignard addition to a C-cyclopropylaldonitrone, C-[cis-2-(N,N-diethyl-carbamoyl)-trans-2-phenylcyclopropyl]-N-benzylaldonitrone (1), stereoselectively gave the anti-product 3, in which the stereoselectivity was particularly high
