81073-10-1Relevant academic research and scientific papers
Synthesis of P-chiral enephosphonic acid derivatives
Grison, Claude,Comoy, Corinne,Chatenet, David,Coutrot, Philippe
, p. 83 - 97 (2007/10/03)
An efficient and convenient synthesis of chiral enephosphonic acid derivatives (enephosphonates, enephosphonamides, enephosphinates) was reported by a two-step procedure involving alkylidenediphosphorylation of nucleophiles followed by a Horner-Emmons olefination. Depending on the selected strategy, the synthesis could be executed according to a one-pot or a twostep reaction sequence. Regioselectivity of Horner-Emmons reaction and 31P-NMR study of diphosphorylated anions were described.
BASE-CATALYZED CONDENSATION OF BIS(DIETHYLPHOSPHONOMETHYL)PHOSPHINIC AMIDES WITH ALDEHYDES
Gilmore, Franklin W.,Park, Joon Sup
, p. 287 - 292 (2007/10/02)
The reaction of the mono anion of bis(diethylphosphonomethyl)phosphinic amides (3) with aldehydes gives varying amounts of diethyl alkyl- or arylethenylphosphonates (10) and diethylphosphonomethylalkyl- or arylethenylphosphinic amides (7).When R in 3 is N
