81227-39-6

Basic information

• Product Name: methyl 2,3,6-trideoxy-5-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-α-L-lyxo-hexofuranoside
• CAS NO: 81227-39-6
• Molecular Weight: 406.315
• Mol File: 81227-39-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2,3,6-trideoxy-5-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-α-L-lyxo-hexofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3,6-trideoxy-5-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-α-L-lyxo-hexofuranoside(81227-39-6)
• EPA Substance Registry System: methyl 2,3,6-trideoxy-5-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-α-L-lyxo-hexofuranoside(81227-39-6)

Safety Data

• Hazardous Substances Data: 81227-39-6(Hazardous Substances Data)

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 81227-38-5 methyl 2,3,6-trideoxy-3-(trifluoroacetamido)-α-L-lyxo-hexofuranoside 
• 78841-78-8 methyl 3-azido-5-O-benzyl-2,3,6-trideoxy-α-L-lyxo-hexofuranoside 
• 105497-60-7 methyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexofuranoside 
• 87536-37-6 methyl 2,3,6-trideoxy-3-trifluoroacetamido-5-O-trifluoracetyl-α-L-lyxo-hexofuranoside 
• 81227-37-4 2,3,6-trideoxy-3-(trifluoroacetamido)-L-lyxo-hexose diethyl dithioacetal 
• 51996-45-3 2,3,6-Trideoxy-3-trifluoroacetamido-L-lixo-hexopyranose 

Downstream Products

• 81275-35-6 1-O-acetyl-2,3,6-trideoxy-5-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-L-lyxo-hexofuranoside 

Relevant articles and documents

Cytostatic activity of daunorubicin analogs containing daunosamine as furanoside

This paper describes the synthesis of daunorubicin (daunomycin) analogs, differing from the natural antibiotics in the ring size of the sugar moiety (furanosides instead of pyranosides). Both, the 5-O-methyl derivative 7 as well as the daunosaminofuranoside 16 were less active cytostatics than doxorubicin (adriamycin), but 16 was also much less toxic, consequently its therapeutic index is more favourable.