81244-12-4

Upstream product

• 69304-45-6 3',5'-O-(1,1,3,3-tetra-isopropyldisiloxane-1,3-diyl)adenosine 
• 81243-94-9 (2R,3R,3aS,9aR)-5,5,7,7-Tetraisopropyl-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-ol 
• 81243-98-3 [(4-Methoxy-phenyl)-diphenyl-methyl]-{9-[(2R,3R,3aR,9aR)-5,5,7,7-tetraisopropyl-3-(tetrahydro-pyran-2-yloxy)-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl]-9H-purin-6-yl}-amine 
• 81244-04-4 (2R,3R,4R,5R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-ol 
• 14470-28-1 mono-4-methoxytrityl chloride 
• 81244-01-1 (2R,3R,4R,5R)-2-Hydroxymethyl-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-ol 
• 110-87-2 3,4-dihydro-2H-pyran 
• 81244-08-8 Dithiophosphoric acid O-[(2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester 
• 121-44-8 triethylamine 

Downstream Products

• 90813-98-2 C₁₀₉H₁₀₄N₁₀O₁₆P₂S₃ 

Relevant academic research and scientific papers

Chemical Synthesis of Capped Oligoribonucleotides, m7G5'pppAUG and m7G5'pppAUGACC

The fully-protected pAUG(15) and pAUGACC(21) were synthesized by the phosphotriester approach where the phenylthio group was employed as the internal and 5'-terminal phosphate-protecting groups.The partially unblocked oligomers (32) and (33), obtained by

SYNTHESIS OF OLIGORIBONUCLEOTIDES BY USE OF S,S-DIPHENYL N-MONOMETHOXYTRITYL RIBONUCLEOSIDE 3'-PHOSPHORODITHIOATES

The fully protected ribonucleotide units (6a-d) have been synthesized in 42-62 percent overall yields by the 5- or 6-step reactions.The dimethoxtrityl, monomethoxytrityl, tetrahydropyran-2-yl, and phenylthio groups were introduced onto the 5'-OH, exo-amin