81245-92-3

Upstream product

• 34231-78-2 3-formylphenyl acetate 
• 3415-35-8 4-methyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-dione 
• 25673-61-4 1-acetyl-trans-3-(3-acetoxybenzylidene)-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione 
• 81245-93-4 2-bromo-N-(methoxymethyl)-N-aniline 
• 25673-60-3 trans-3-(3-acetoxybenzylidene)-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione 
• 81255-43-8 2-bromo-N-aniline 
• 81245-95-6 1-(methoxymethyl)-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione 
• 81245-94-5 2-bromo-N-(methoxymethyl)-N-(N-methylglycyl)aniline 
• 81246-00-6 dl-cyclopenol O-acetate 

Relevant academic research and scientific papers

New Synthesis of Diazepam and the Related 1,4-Benzodiazepines by means of Palladium-Catalyzed Carbonylation

A new synthesis of diazepam (5) was achieved by application of palladium-catalyzed carbonylation to the compound 3 prepared from o-bromoaniline derivative 1 and the amino acid 2, and this procedure was also used for the synthesis of poisonous metabolites