81250-28-4 Usage
Type
Xanthine derivative
Function
Non-selective inhibitor of phosphodiesterases and adenosine receptors
Application
Scientific research tool for studying cAMP-dependent signaling pathways
Mechanism of Action
Increases intracellular cAMP levels by inhibiting its degradation
Effect on Signaling Pathways
Activation of protein kinase A and downstream signaling cascades
Therapeutic Potential
Being investigated for treating asthma, chronic obstructive pulmonary disease, and hypertension
Additional Use
Pharmacological tool to enhance the effects of other drugs and compounds
Importance
Valuable tool in biomedical and pharmaceutical research due to its wide range of biological activities
Check Digit Verification of cas no
The CAS Registry Mumber 81250-28-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,2,5 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 81250-28:
(7*8)+(6*1)+(5*2)+(4*5)+(3*0)+(2*2)+(1*8)=104
104 % 10 = 4
So 81250-28-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H22N4O2/c1-8(2)6-17-12-11(15-10(5)16-12)13(19)18(14(17)20)7-9(3)4/h8-9H,6-7H2,1-5H3,(H,15,16)
81250-28-4Relevant articles and documents
Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent
-
, (2008/06/13)
The invention relates to the use of 1,3-diisobutyl-8--methylxanthine, or its pharmaceutically acceptable salts, for the treatment or prophylaxis of acute or chronic obstructive airways disease and allergic asthma. The invention also relates to a pharmaceutical composition of an aerosol containing 1,3-diisobutyl-8-methylxanthine, ethanol, sorbitan oleate and one or more freons.
Di- or trisubstituted xanthines with neuroleptic properties and composition
-
, (2008/06/13)
The invention relates to xanthines corresponding to the formula STR1 and physiologically acceptable salts thereof, in which R1 represents C2 -C4 -alkyl, C3 -C4 -isoalkyl, CH2 -(C2 -C3 -alkenyl) or CH2 -(C3 -isoalkenyl); R3 represents C3 -C5 -alkyl, C3 -C5 -isoalkyl, CH2 -(C2 -C4 -alkenyl) or CH2 -(C3 -C4 -isoalkenyl); R8 represents H, methyl or ethyl; with the proviso that (1) when R8 represents H, R1 is allyl and (2) R1 and R3 cannot both represent butyl or allyl at the same time. The compounds show non-specific or anxiolytic sedative activity.
