812640-47-4Relevant academic research and scientific papers
Integrating chemosensors for amine-containing compounds into cross-linked dendritic hosts
Mertz, Eric,Elmer, Stephanie L.,Balija, Amy M.,Zimmerman, Steven C.
, p. 11191 - 11204 (2007/10/03)
Trifluoroacetylazo dye 1, a known chemosensor for amines, has been integrated into cross-linked dendrimer hosts. Thus, boronic acid 16 was linked to iododye 9 via a Suzuki coupling reaction. In situ deprotection and alkylation with dendrons 3 and 4, conta
Cross-linked dendrimer hosts containing reporter groups for amine guests
Mertz, Eric,Zimmerman, Steven C.
, p. 3424 - 3425 (2007/10/03)
The integration of a chromogenic reporter group into the recently reported (Zimmerman, S. C.; Wendland, M. S.; Rakow, N. A.; Zharov, I.; Suslick, K. S. Nature 2002, 418, 399-403) monomolecular imprinting approach is described. The resulting highly cross-linked, macromolecular hosts show rapid, selective, high affinity, two-point binding of straight-chain diamine guests. Over longer times, the hosts are more promiscuous, binding a broader range of diamines. A rigorous test of imprinting was performed wherein the cross-reactivities of two dendrimers derived from different templates are compared. The test reveals a guest-dependent kinetic binding effect masquerading as evidence of a highly selective two-point imprinting process. Copyright
