25245-27-6Relevant academic research and scientific papers
Synthesis of a TREN in which the aryl substituents are part of a 45 atom macrocycle
Cain, Matthew F.,Forrest, William P.,Peryshkov, Dmitry V.,Schrock, Richard R.,Mueller, Peter
, p. 15338 - 15341 (2013)
A substituted TREN has been prepared in which the aryl groups in (ArylNHCH2CH2)3N are substituted at the 3- and 5-positions with a total of six OCH2(CH2) nCH=CH2 groups (n = 1, 2
Participation of Halogen Atoms in Hydrogen Transfer Between Remote Positions in Gas-phase Ionized Isomeric Haloresorcinols
Weisz, Adrian,Andrzejewski, Denis,Mandelbaum, Asher
, p. 891 - 895 (1992)
Mono, di- and trihaloresorcinols substituted by a halogen atom at position 2 exhibit a highly specific elimination of H2O on electron impact ionization and under conditions of collisionally induced dissociation (CID).The high isomer specificity suggests t
A pH-Responsive DNAsome from the Self-Assembly of DNA–Phenyleneethynylene Hybrid Amphiphile
Albert, Shine K.,Golla, Murali,Thelu, Hari Veera Prasad,Krishnan, Nithiyanandan,Varghese, Reji
, p. 8348 - 8352 (2017)
A pH-responsive DNAsome derived from the amphiphilicity-driven self-assembly of DNA amphiphile containing C-rich DNA sequence is reported. The acidification of DNAsome induces a structural change of C-rich DNA from random coil to an i-motif structure that
Self-assembly of DNA-oligo(p-phenylene-ethynylene) hybrid amphiphiles into surface-engineered vesicles with enhanced emission
Albert, Shine K.,Thelu, Hari Veera Prasad,Golla, Murali,Krishnan, Nithiyanandan,Chaudhary, Soma,Varghese, Reji
, p. 8352 - 8357 (2014)
Surface-addressable nanostructures of linearly π-conjugated molecules play a crucial role in the emerging field of nanoelectronics. Herein, by using DNA as the hydrophilic segment, we demonstrate a solid-phase "click" chemistry approach for the synthesis
Synthesis of chloro-substituted 6H-dibenzo[b,d]pyran-6-one natural products, graphislactone G, and palmariols A and B
Abe, Hitoshi,Horino, Yoshikazu,Imai, Haruka,Jeelani, Ishtiaq,Yonoki, Atsuro
, p. 781 - 788 (2021/08/06)
A palladium-mediated intramolecular aryl–aryl coupling reaction was applied to the total synthesis of the bioactive natural products, graphislactone G (1), and palmariols A (2) and B (3), which possess an unusual chloro-subsutituent on the 6H-dibenzo[b,d]
Organophotoredox-catalyzed intermolecular Oxa-[4+2] cycloaddition reactions
Tanaka, Kenta,Omata, Daichi,Asada, Yosuke,Hoshino, Yujiro,Honda, Kiyoshi
, p. 10669 - 10678 (2019/08/22)
An intermolecular oxa-[4+2] cycloaddition reaction promoted by a thioxanthylium photoredox catalyst under irradiation with green light has been developed. The reaction of ortho-quinone methides with styrenes smoothly affords the desired cycloadducts. Espe
A Revised Modular Approach to (–)-trans-Δ8-THC and Derivatives Through Late-Stage Suzuki–Miyaura Cross-Coupling Reactions
Bloemendal, Victor R. L. J.,Sondag, Daan,Elferink, Hidde,Boltje, Thomas J.,van Hest, Jan. C. M.,Rutjes, Floris P. J. T.
, p. 2289 - 2296 (2019/04/03)
A revised modular approach to various synthetic (–)-trans-Δ8-THC derivatives through late-stage Suzuki–Miyaura cross-coupling reactions is disclosed. Ten derivatives were synthesized allowing both sp2- and sp3-hybridized cross-coupling partners with minimal β-hydride elimination. Importantly, we demonstrate that a para-bromo-substituted THC scaffold for Suzuki–Miyaura cross-coupling reactions has been initially reported incorrectly in recent literature.
Synthesis of Indole-, Benzo[ b]thiophene-, and Benzo[ b]selenophene-Based Analogues of the Resveratrol Dimers Viniferifuran and (±)-Dehydroampelopsin B
Krzyzanowski, Adrian,Saleeb, Michael,Elofsson, Mikael
supporting information, p. 6650 - 6654 (2018/10/25)
A convenient synthetic strategy to obtain viniferifuran and (±)-dehydroampelopsin B analogues based on the heterocyclic cores of indole, benzo[b]thiophene, and benzo[b]selenophene is presented. The key transformations utilized in the described syntheses include Sonogashira couplings, Cacchi and alkyne electrophilic cyclizations, Horner-Wadsworth-Emmons (HWE) reaction, chemoselective Suzuki-Miyaura couplings, and acid-promoted intramolecular cyclization to form the seven-membered ring of (±)-dehydroampelopsin B.
Synthesis method of resveratrol
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Paragraph 0039; 0040, (2018/05/03)
The invention provides a synthesis method of resveratrol, and belongs to the technical field of natural product synthesis. The synthesis method comprises the following steps: with 3,5-dimethoxy benzoic acid as a raw material, generating 3,5-dimethoxy benzoyl chloride (12) through an acylating chlorination reaction; generating 3,5-dimethoxy benzamide (13) through an amidation reaction of the (12);generating 3,5-dimethoxyaniline (14) through a Hofmann degradation reaction of the (13); generating 3,5-dimethoxy iodobenzene (15) through a Sandmeyer reaction on the (14); generating 3,5,4'-trimethoxy diphenylethene (31) through a reaction between the (15) and p-methoxystyrene (23), and performing demethylation of the (31) to finally obtain resveratrol (1), wherein total yield is 23.3%. Accordingto the method, the adopted reagent is cheap and easily available, aftertreatment is simple, and two expensive intermediates for Heck reaction are synthesized by adopting cheap raw materials. A new synthesis method is provided for synthesizing resveratrol.
Green-light-driven thioxanthylium-based organophotoredox catalysts: Organophotoredox promoted radical cation Diels-Alder reaction
Tanaka, Kenta,Kishimoto, Mami,Sukekawa, Mayumi,Hoshino, Yujiro,Honda, Kiyoshi
supporting information, p. 3361 - 3364 (2018/08/06)
Thioxanthylium-based organophotoredox catalysts that operate under irradiation with green light have been developed. These catalysts present high excited-state reduction potentials (E0′(C?/C?) = +1.79–1.94 V vs SCE). They
