64339-43-1Relevant academic research and scientific papers
Friedel–Crafts approach to the one-pot synthesis of methoxy-substituted thioxanthylium salts
Tanaka, Kenta,Tanaka, Yuta,Kishimoto, Mami,Hoshino, Yujiro,Honda, Kiyoshi
, p. 2105 - 2112 (2019)
An efficient synthesis of methoxy-substituted thioxanthylium salts has been developed. The reaction of diaryl sulfides with benzoyl chlorides in the presence of TfOH smoothly proceeded to give the desired thioxanthylium salts in good yields. In their UV–vis spectra, the maximum absorption wavelengths of methoxy-functionalized thioxanthylium salts were observed at around 460 nm, which show a drastic red shift compared to the parent thioxanthylium salts. The present reaction provides a versatile access to functionalized thioxanthylium salts, and therefore it constitutes a promising tool for the synthesis of biologically and photochemically active molecules.
Synthesis and initial biological evaluation of myxocoumarin B
Müller, Jonas I.,Kusserow, Kalina,Hertrampf, Gesa,Pavic, Aleksandar,Nikodinovic-Runic, Jasmina,Gulder, Tobias A. M.
supporting information, p. 1966 - 1969 (2019/02/20)
The myxocoumarins A and B from Stigmatella aurantiaca MYX-030 are natural products featuring unusual nitro- and long-chain alkyl substitution. While myxocoumarin A was shown to exhibit strong antifungal properties, the antifungal potential of myxocoumarin
A Revised Modular Approach to (–)-trans-Δ8-THC and Derivatives Through Late-Stage Suzuki–Miyaura Cross-Coupling Reactions
Bloemendal, Victor R. L. J.,Sondag, Daan,Elferink, Hidde,Boltje, Thomas J.,van Hest, Jan. C. M.,Rutjes, Floris P. J. T.
, p. 2289 - 2296 (2019/04/03)
A revised modular approach to various synthetic (–)-trans-Δ8-THC derivatives through late-stage Suzuki–Miyaura cross-coupling reactions is disclosed. Ten derivatives were synthesized allowing both sp2- and sp3-hybridized cross-coupling partners with minimal β-hydride elimination. Importantly, we demonstrate that a para-bromo-substituted THC scaffold for Suzuki–Miyaura cross-coupling reactions has been initially reported incorrectly in recent literature.
A pH-Responsive DNAsome from the Self-Assembly of DNA–Phenyleneethynylene Hybrid Amphiphile
Albert, Shine K.,Golla, Murali,Thelu, Hari Veera Prasad,Krishnan, Nithiyanandan,Varghese, Reji
supporting information, p. 8348 - 8352 (2017/06/28)
A pH-responsive DNAsome derived from the amphiphilicity-driven self-assembly of DNA amphiphile containing C-rich DNA sequence is reported. The acidification of DNAsome induces a structural change of C-rich DNA from random coil to an i-motif structure that
SHIP1 MODULATORS AND METHODS RELATED THERETO
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, (2014/07/23)
Compounds of formula (I): [Formula should be inserted here]; where [Formula should be inserted here], n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising a compound of formula (I) in combination with a pharmaceutically acceptable carrier or diluent are also disclosed, as are methods of SHIP1 modulation by administration of such compounds to an animal in need thereof.
Self-assembly of DNA-oligo(p-phenylene-ethynylene) hybrid amphiphiles into surface-engineered vesicles with enhanced emission
Albert, Shine K.,Thelu, Hari Veera Prasad,Golla, Murali,Krishnan, Nithiyanandan,Chaudhary, Soma,Varghese, Reji
supporting information, p. 8352 - 8357 (2014/08/18)
Surface-addressable nanostructures of linearly π-conjugated molecules play a crucial role in the emerging field of nanoelectronics. Herein, by using DNA as the hydrophilic segment, we demonstrate a solid-phase "click" chemistry approach for the synthesis
Synthesis of a TREN in which the aryl substituents are part of a 45 atom macrocycle
Cain, Matthew F.,Forrest, William P.,Peryshkov, Dmitry V.,Schrock, Richard R.,Mueller, Peter
, p. 15338 - 15341 (2013/11/06)
A substituted TREN has been prepared in which the aryl groups in (ArylNHCH2CH2)3N are substituted at the 3- and 5-positions with a total of six OCH2(CH2) nCH=CH2 groups (n = 1, 2
Sol-gel immobilized aryl iodides for the catalytic oxidative α-tosyloxylation of ketones
Guo, Wusheng,Monge-Marcet, Amàlia,Catto?n, Xavier,Shafir, Alexandr,Pleixats, Roser
, p. 192 - 199 (2013/02/25)
New hybrid silica materials M1-M4, derived from mono and bis-silylated aryl iodides, have been prepared via sol-gel processes, either by the hydrolytic polycondensation of a bis-silylated monomer or by the co-gelification of a monosilylated precursor with
CYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
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Page/Page column 92, (2013/07/05)
The present invention provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, mucositis, an ophthalmic infection, an otic infection, a cancer, or a Mycobacterium infection; inhibiting the growth of a Mycobacterium species; modulating an immune response in a mammal; or antagonizing unfractionated heparin, low molecular weight heparin, or a heparin/low molecular weight heparin derivative.
PHENANTHROl[1,10,9,8-C,D,E,F,G]CARBAZOLE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS
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, (2012/06/16)
The invention relates to novel phenanthro[1,10,9,8-c,d,e,f,g]carbazole polymers, methods and materials for their preparation, their use as semiconductors in organic electronic (OE) devices, and to OE devices comprising these polymers.
