812673-60-2

Upstream product

• 23464-17-7 1,3-diphenylpropane-1,2-dione 
• 861586-97-2 2,3-dibromo-2-methoxy-1,3-diphenyl-propan-1-one 
• 5411-12-1 chalcone epoxide 
• 64-17-5 ethanol 
• 10035-10-6 hydrogen bromide 

Downstream Products

• 855754-86-8 α,β-diacetoxy-chalcone 
• 5784-78-1 phenyl-(3-phenyl-quinoxalin-2-yl)-methanone 

Relevant academic research and scientific papers

LiBr/β-CD/IBX/H2O-DMSO: A new approach for one-pot biomimetic regioselective ring opening of chalcone epoxides to bromohydrins and conversion to 1,2,3-triketones

Highly regioselective ring cleavage of chalcone epoxides to bromohydrins has been carried out in good yields with LiBr in the presence of β-CD using DMSO-H2O as solvent system. The ring-opened product, i.e., bromohydrin, was well adapted to IBX-mediated oxidation in such a fashion that the bromohydrins are transformed to their corresponding 1,2,3-triketones in moderate-to-good yields in one pot.