81280-45-7

Basic information

• Product Name: 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)
• Synonyms: 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)
• CAS NO: 81280-45-7
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.1745
• Mol File: 81280-45-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)(81280-45-7)
• EPA Substance Registry System: 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)(81280-45-7)

Safety Data

• Hazardous Substances Data: 81280-45-7(Hazardous Substances Data)

Upstream product

• 765-69-5 2-Methylcyclopentane-1,3-dione 
• 6089-04-9 3-(tetrahydropyran-2'-yloxy)propyne 
• 56778-49-5 3-iodo-2-methyl-2-cyclopentenone 

Downstream Products

• 345620-19-1 E-triphenylphosphonium 4-<3-(2-methyl-3-oxocyclopent-1-enyl)bicyclo<2.2.1>hepta-2,5-dien-2-yl>-2-oxobut-2-enylide 
• 81280-46-8 (2-Methyl-3-oxo-cyclopent-1-enyl)-propynal 

Relevant articles and documents

Investigation of an Electrocyclisation Route to the 7bH-Cyclopentindene System

An approach to the synthesis of derivatives of 7bH-cyclopentindene ring system (1) has been explored in which two of the three rings are constructed by cyclisation reactions.The acetylenic alcohol (7) was prepared by coupling of 3-iodo-2-methylcyclopent-2-en-1-one (6) with the copper(I) salt of prop-2-ynyl alcohol tetrahydropyranyl ether.This was then converted into the Z,E-trienedione (2).On heating, this compound failed to undergo cyclisation; the only reaction observed was its isomerisation to the E,E-trienedione (10).Under forcing conditions it gave only indan-1-one.The cis-double bond of the trienedione system was fixed by incorporating it into a bicycloheptadiene system.Two such derivatives, (14) and (15), were prepared; both underwent smooth electrocyclic ring-closure on heating and the ylide (15) also cyclised further to give compound (19), which incorporates the required 7bH-cyclopentindene skeleton.