81303-65-3

Basic information

• Product Name: 4-Ethyl hydrogen 1-methyl-1h-pyrazole-4,5-dicarboxylate , 97%
• Synonyms: 4-Ethyl hydrogen 1-methyl-1h-pyrazole-4,5-dicarboxylate , 97%;4-(Ethoxycarbonyl)-1-Methyl-1H-pyrazole-5-carboxylic acid;1-Methyl-1H-pyrazole-4,5-dicarboxylic acid 4-ethyl ester;2-Methyl-2H-pyrazole-3,4-dicarboxylic acid 4-ethyl ester;4-Ethoxycarbonyl-2-methyl-pyrazole-3-carboxylic acid
• CAS NO: 81303-65-3
• Molecular Formula: C₈H₁₀N₂O₄
• Molecular Weight: 198.176
• Mol File: 81303-65-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Ethyl hydrogen 1-methyl-1h-pyrazole-4,5-dicarboxylate , 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Ethyl hydrogen 1-methyl-1h-pyrazole-4,5-dicarboxylate , 97%(81303-65-3)
• EPA Substance Registry System: 4-Ethyl hydrogen 1-methyl-1h-pyrazole-4,5-dicarboxylate , 97%(81303-65-3)

Safety Data

• Statements: 22-36/37/38
• Safety Statements: 22-26-36/37/39
• Hazardous Substances Data: 81303-65-3(Hazardous Substances Data)

Usage

General Description

4-Ethyl hydrogen 1-methyl-1h-pyrazole-4,5-dicarboxylate, 97% is a chemical compound with a purity of 97%. It is a derivative of pyrazole and dicarboxylic acid, with an ethyl group and a methyl group attached to the pyrazole ring. 4-Ethyl hydrogen 1-methyl-1h-pyrazole-4,5-dicarboxylate , 97% has potential applications in the pharmaceutical and chemical industries, as it may be used as a building block for the synthesis of various drugs and other organic compounds. Its high purity of 97% makes it suitable for use in research and development, as well as in the production of pharmaceuticals and other specialized chemical products.

Upstream product

• 1564248-35-6 (Z)-diethyl 2-((2-([tert-butoxy]carbonyl)-2-methylhydrazinyl)methylene)-3-oxosuccinate 
• 130187-88-1 2-[1-(dimethylamino)methylidene]-3-oxosuccinic acid diethyl ester 
• 10514-61-1 2-methyl-2H-pyrazole-3,4-dicarboxylic acid diethyl ester 

Downstream Products

• 1278406-76-0 5-(6-Cyano-2-phenyl-imidazo[1,2-a]pyridin-7-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 1278407-29-6 4-(Azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid (6-bromo-2-phenyl-imidazo[1,2-a]pyridin-7-yl)-amide 
• 1278407-64-9 5-(6-bromo-2-phenyl-imidazo[1,2-a]pyridin-7-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 1278407-65-0 5-(6-bromo-2-phenyl-imidazo[1,2-a]pyridin-7-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid 
• 1380330-03-9 1-methyl-5-(2-phenylimidazo[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid ethyl ester 
• 1278407-56-9 1-methyl-5-(2-phenyl-imidazo[1,2-a]pyridin-7-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid 
• 1278406-72-6 1-methyl-5-(2-phenylimidazo[1,2-a]pyridin-7-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid ethyl ester 
• 81303-52-8 ethyl 5-carbamoyl-1-methyl-1H-pyrazole-4-carboxylate 
• 1380329-86-1 2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)amide] 
• 1380329-78-1 4-(azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid (2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)amide 
• 1278406-65-7 2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide] 
• 1278406-88-4 4-(azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid (2-phenylimidazo[1,2-a]pyridin-7-yl)amide 
• 1428747-20-9 1-methyl-5-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-6-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid ethyl ester 
• 1426444-25-8 ethyl 1-methyl-5-(2-(5-methyl-2-phenyloxazol-4-yl)ethylcarbamoyl)-1H-pyrazole-4-carboxylate 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID DERIVATIVES

The present invention relates to a novel process for the preparation of a pyrazole carboxylic acid derivative of the formula wherein R1 is C1-7-alkyl and R3 is C1-7-alkyl which is optionally substituted with halogen or C1-4-alkoxy. The pyrazole carboxylic acid derivative of the formula I can be used as building block in the preparation of pharmaceutically active principles e.g. for compounds acting as phosphodiesterase (PDE) inhibitors, particularly PDE10 inhibitors. PDE10 inhibitors have the potential to treat psychotic disorders like schizophrenia.

NOVEL IMIDAZOPYRIDINES

The invention is concerned with novel imidazopyridine derivatives of formula (I) wherein R1, R2, R3, R4, R5 and A are as defined in the description and in the claims, as well as physiologically accept

N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDE DERIVATIVES AND THEIR USE AS PDE10A INHIBITORS

The invention is concerned with novel imidazopyrimidine derivatives of formula (I) wherein R1, R2 and R8 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDEIOA and used as medicaments.