81309-22-0

Basic information

• Product Name: C₁₉H₁₄BrNO₅
• Synonyms: C₁₉H₁₄BrNO₅
• CAS NO: 81309-22-0
• Molecular Weight: 416.228
• Mol File: 81309-22-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₄BrNO₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₄BrNO₅(81309-22-0)
• EPA Substance Registry System: C₁₉H₁₄BrNO₅(81309-22-0)

Safety Data

• Hazardous Substances Data: 81309-22-0(Hazardous Substances Data)

Upstream product

• 2199-87-3 6-bromocoumarin-3-carboxylic acid 
• 1761-61-1 5-bromosalicyclaldehyde 
• 2199-90-8 ethyl 6-bromo-2-oxo-2H-chromene-3-carboxylate 
• 2199-94-2 6-bromo-2-oxo-2H-1-benzopyran-3-carboxylic acid chloride 
• 94-09-7 p-aminoethylbenzoate 

Downstream Products

• 312756-47-1 C₁₇H₁₀BrNO₅ 

Relevant articles and documents

A novel class of selective anti-Helicobacter pylori agents 2-oxo-2H-chromene-3-carboxamide derivatives

A novel class of selective anti-Helicobacter pylori agents, 2-oxo-2H-chromene-3-carboxamide derivatives, were prepared and evaluated for their anti-bacterial activity. All synthesized compounds showed little or no activity against different species of Gram-positive and Gram-negative bacteria and against various strains of pathogenic fungi. Some of them exhibited a potent and specific inhibitory effect on the growth of H. pylori, including metronidazole-resistant strains, in the 0.0039-16 μg/mL MIC range. A cytotoxic screening by the Trypan blue dye exclusion assay was also carried out on the most active compounds as anti-H. pylori agents. Among the derivatives examined for their cytotoxic potential, a number of them induced low cytotoxic effects.