81327-28-8

Basic information

• Product Name: tert-butyl 2-(5-chloro-2-nitrophenyl)ethanoate
• Synonyms: tert-butyl 2-(5-chloro-2-nitrophenyl)ethanoate
• CAS NO: 81327-28-8
• Molecular Weight: 271.7
• Mol File: 81327-28-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-(5-chloro-2-nitrophenyl)ethanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(5-chloro-2-nitrophenyl)ethanoate(81327-28-8)
• EPA Substance Registry System: tert-butyl 2-(5-chloro-2-nitrophenyl)ethanoate(81327-28-8)

Safety Data

• Hazardous Substances Data: 81327-28-8(Hazardous Substances Data)

Upstream product

• 321745-86-2 2-tert-butoxy-2-oxoethylzinc chloride 
• 63860-31-1 2-bromo-4-chloro-1-nitrobenzene 
• 89278-15-9 Dimethylthiocarbamoylsulfanyl-acetic acid tert-butyl ester 
• 100-00-5 4-chlorobenzonitrile 
• 107-59-5 tert-Butyl chloroacetate 
• 540-88-5 acetic acid tert-butyl ester 

Relevant articles and documents

AMINOMETHYL-BIARYL DERIVATIVES AS COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF

The present invention provides a compound of formula (I), a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical com

Vicarious Nucleophilic Substitution of Hydrogen in Nitroarenes with α-Substituted Nitriles and Esters. Direct α-Cyanoalkylation and α-Carbalkoxyalkylation of Nitroarenes

Carbanions generated from alkanenitriles bearing α-chloro, α-OR, or α-SR groups and from aliphatic esters bearing α-SR groups react with mononitroarenes to replace hydrogen atoms of the nitroaromatic ring ortho or para to the nitro group with α-cyanoalkyl or α-carbalkoxyalkyl substituents.The nucleophilic replacement of hydrogen with such carbanions proceeds faster than substitution of halogen ortho or para to the nitro group.

AROMATIC NUCLEOPHILIC SUBSTITUTION BY HYDRIDE ELIMINATION

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