81347-74-2Relevant academic research and scientific papers
Iron-Catalyzed Electrophilic Amination of Sodium Sulfinates with Anthranils
Liang, Baihui,Huang, Junjie,Zhu, Weidong,Li, Yawen,Jiang, Lanping,Gao, Yang,Xie, Feng,Li, Yibiao,Chen, Xiuwen,Zhu, Zhongzhi
, p. 1466 - 1473 (2021/02/09)
A practical method for the synthesis of N-(2-carbonylaryl) benzenesulfonamides via an iron-catalyzed electrophilic amination of sodium sulfinates with anthranils is described. This redox-neutral transformation has high atom efficiency and is achieved under simple and mild reaction conditions. A wide range of anthranils and sodium sulfinates were compatible in this transformation. Moreover, the synthetic potential of this methodology was further demonstrated by the synthesis of various useful N-heterocycles and derivatives.
Synthesis method of o-acylaniline sulfonamide compound
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Paragraph 0139-0144, (2020/10/30)
The invention discloses a synthesis method of a o-acylaniline sulfonamide compound. The preparation method is characterized by comprising the following steps: mixing a benzisoxazole compound as shownin a chemical formula I, a sodium sulfinate compound as shown in a chemical formula II, a metal catalyst and a solvent, and reacting to obtain the o-acylaniline sulfonamide compound as shown in a chemical formula III, in the formula, R1 is a monosubstituted or polysubstituted group on a benzene ring. The synthesis method can be used for efficiently synthesizing the o-acylaniline sulfonamide compound, has the advantages of simple synthesis steps, safety in operation, good compatibility of the synthesis method to functional groups and high atom economy, and is easy for industrial synthesis.
Bis-aryl sulfonamides
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, (2008/06/13)
Compounds are provided that act as potent antagonists of chemokine receptors. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor-mediated diseases, and as controls in assays for the identification of chemokine antagonists.
1H, 13C and 15N NMR spectral and X-ray structural studies of 2-arylsulfonylamino-5-chlorobenzophenones
Kolehmainen,Nissinen,Janota,Gawinecki,Osmialowski
, p. 889 - 894 (2007/10/03)
Six 2-(4-R-phenylsulfonylamino)-5-chlorobenzophenones were prepared and their 1H, 13C and 15N NMR spectra recorded and assigned. The dependence between the chemical shift of the amide proton and Hammett σ substituent const
Benzodiazepine intermediates
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, (2008/06/13)
A compound of the formula STR1 wherein X and Y are independently selected from hydrogen, halogen, trifluoromethyl, nitro, C1 to C6 alkyl and C1 to C6 alkoxy, and Z is C1 to C6 alkyl or hydrogen is disclosed.
