81401-31-2Relevant articles and documents
PYRIMIDINE DERIVATIVES. 56. METHOD FOR THE SYNTHESIS OF THIENOPYRIMIDINE
Melik-Ogandzhanyan, R. G.,Gapoyan, A. S.,Khachatryan, V. E.,Mirzoyan, V. S.
, p. 100 - 102 (1982)
A new scheme was developed for the synthesis of 2,4-dimethyl-5,6-dihydro-6-bromomethylthienopyrimidine by bromination of the corresponding 5-allyl-6-mercaptopyrimidine.It is shown that when the bromomethyl derivative is treated with sodium methoxide a molecule of hydrogen bromide is split out to give 2,4,6-trimethylthienopyrimidine.The structures of the synthesized compounds were proved by PMR spectroscopy and mass spectrometry.