78304-54-8Relevant academic research and scientific papers
Synthesis and Structure of New Substituted Pyrimidinone with Unsaturated Side Chain
Harutyunyan,Gukasyan,Panosyan,Tamazyan,Aivazyan,Danagulyan
, p. 771 - 775 (2018)
Melting of a mixture of 5-substituted 2,4-dimethyl-1,6-dihydropyrimidin-6-ones with cinnamic aldehyde, 1-methylindoline-2,3-dione and 6-methoxy-2-chloroquinoline-3-carbaldehyde in the presence of ZnCl2 led to the formation of substituted pyrimidines with conjugated bonds in the position 2. The structure of synthesized compounds as 2-isomers was confirmed by 2D 1H NMR NOESY data.
Substituted aminopyrimidines as antihypertensives
-
, (2008/06/13)
This invention relates to substituted 4-aminopyrimidines, which by virtue of their ability to antagonize angiotensin II are useful for the treatment of hypertension, congestive heart failure, and restenosis. The compounds are also useful for reducing lipi
