81451-83-4Relevant academic research and scientific papers
Inter- and intramolecular addition of ester anions to nicotinium salts. A facile approach to nauclefine and ellipticine derivatives
Wanner,Koomen,Pandit
, p. 3673 - 3681 (2007/10/02)
Reaction of ester anions with 1-(2'-indolyl-ethyl)nicotinium chloride and 1-(1'-methyl-2'-indolylethyl)-nicotinium chloride leads to 2,7-naphthyridine-1,3-diones. Acid catalyzed cyclization of the latter yield pentacyclic napthyridocarboline derivatives.
A NEW APPROACH TO ELLIPTICINE ANALOGUES; SYNTHESIS OF 11-HYDROXY-5,6-DIMETHYLPYRIDOCARBAZOLE
Wanner, Martin J.,Koomen, Gerrit-Jan,Pandit, Upendra K.
, p. 59 - 62 (2007/10/02)
2-(2'Indolyl)propionic ester reacts with nicotynoyl chloride to give a pyridyl ketone which, following quaternization and treatment with base, cyclizes to the pyridocarbazole skeleton.
