81512-04-1

Basic information

• Product Name: (2R)-2-[(4-chlorophenyl)amino]-2-phenylpropanenitrile
• CAS NO: 81512-04-1
• Molecular Formula: C₁₅H₁₃ClN₂
• Molecular Weight: 256.7301
• Mol File: 81512-04-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 422.2°C at 760 mmHg
• Flash Point: 209.1°C
• Density: 1.229g/cm³
• Vapor Pressure: 2.46E-07mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: (2R)-2-[(4-chlorophenyl)amino]-2-phenylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-[(4-chlorophenyl)amino]-2-phenylpropanenitrile(81512-04-1)
• EPA Substance Registry System: (2R)-2-[(4-chlorophenyl)amino]-2-phenylpropanenitrile(81512-04-1)

Safety Data

• Hazardous Substances Data: 81512-04-1(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 106-47-8 4-chloro-aniline 
• 536-74-3 phenylacetylene 
• 98-86-2 acetophenone 
• 143-33-9 sodium cyanide 
• 151-50-8 potassium cyanide 
• 20102-12-9 2-hydroxy-2-phenylpropionitrile 

Downstream Products

• 261505-52-6 6-(4-chlorophenyl)-4-hydroxy-7-phenyl-pyrano[3,2-c]pyridine-2,5(6H)-dione 
• 261505-54-8 3-acetyl-1-(4-chlorophenyl)-4-hydroxy-6-phenyl-pyridin-2(1H)-one 
• 175884-42-1 3-(p-chlorophenyl)-5-imino-4-methyl-1,4-diphenyl-imidazolidin-2-one 
• 25287-19-8 N-(1-phenylethylidene)-4-chloroaniline 

Relevant articles and documents

Cuboctahedral [In36(μ-OH)24(NO3)8(Imtb)24]MOF with Atypical Pyramidal Nitrate Ion in SBU: Lewis Acid-Base Assisted Catalysis and Nanomolar Sensing of Picric Acid

A robust and multifunctional cuboctahedral [In36(μ-OH)24(NO3)8(Imtb)24] MOF (In(Imtb)-MOF) with an atypical pyramidal nitrate ion-containing hitherto unknown SBU core [In9(μ-OH)6(NO3)] is reported. The intra- and interlayer nitrate ions adopt pyramidal an

Production of Quaternary α-Aminonitriles by Means of Indium-Catalyzed Three-Component Reaction of Alkynes, Amines, and Trimethylsilyl Cyanide

A novel synthesis of α-aminonitriles is described via an indium-catalyzed three-component coupling reaction of alkynes, amines, and trimethylsilyl cyanide (Me3SiCN). Hydroamination of alkynes with a subsequent nucleophilic addition of Me3

A novel approach to the synthesis of α-aminonitriles using triphenyl-phosphine dibromide under solvent-free conditions

A quick and highly efficient, one-pot, three-component, solvent-free method for the synthesis of α-aminonitriles starting from the corresponding carbonyl compounds, amines, and trimethylisocyanide using triphenylphosphine dibromide, has been developed. Diverse α-aminonitriles have been synthesized in good to excellent yields (80-99%) using a range of aldehydes, ketones and amines. Georg Thieme Verlag Stuttgart · New York.