81512-53-0

Usage

Uses

Used in Chemical Synthesis:
1-(2-chlorophenyl)-N-[2-[(2-chlorophenyl)methylideneamino]ethyl]methanimine is used as a synthetic intermediate for the creation of various complex organic molecules. Its unique structure allows for the formation of new chemical entities with potential applications in different industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(2-chlorophenyl)-N-[2-[(2-chlorophenyl)methylideneamino]ethyl]methanimine is used as a research compound to explore its potential as a building block for the development of new drugs. Its specific properties may contribute to the discovery of novel therapeutic agents.
Used in Material Science:
1-(2-chlorophenyl)-N-[2-[(2-chlorophenyl)methylideneamino]ethyl]methanimine may also find applications in material science, where its unique chemical structure could be utilized to develop new materials with specific properties, such as improved stability or reactivity.
Used in Research and Development:
1-(2-chlorophenyl)-N-[2-[(2-chlorophenyl)methylideneamino]ethyl]methanimine is used as a research tool to study its chemical properties, reactivity, and potential interactions with other molecules. Understanding these aspects can lead to the development of new methodologies and applications in various scientific fields.

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 107-15-3 ethylenediamine 

Downstream Products

• 101792-32-9 2,2'-bis-(2-chloro-phenyl)-2,2'-ethanediyldiamino-di-acetic acid 
• 6241-46-9 N¹-(2-chlorobenzyl)ethane-1,2-diamine 
• 108896-78-2 N¹,N²-bis(2-chlorobenzyl)ethane-1,2-diamine 
• 1327208-48-9 1,1'-(ethane-1,2-diyl)bis(3-chloro-4-(2-chlorophenyl)azetidin-2-one) 
• 81512-17-6 3,3'-(ethane-1,2-diyl)bis(2-(2-chlorophenyl)thiazolidin-4-one) 
• 109744-50-5 W(CO)3Cl(C₆H₄CHNCH₂CH₂NCHC₆H₄Cl) 
• 114024-58-7 {Ag((C₆H₄(Cl)CHNCH₂)2)2}⁽¹⁺⁾*OSO₂CF₃^(1-)={Ag((C₆H₄(Cl)CHNCH₂)2)2}(OSO₂CF₃) 

Relevant academic research and scientific papers

In-vitro antimicrobial screening and coordination behavior of metals based bidentate compounds

By condensing ethylene-1,2-diamine with different aldehydes such as benzaldehyde, 4-chloroacetophenone and 2-chlorobenzaldeyhde within 1:2 molar ratio, resulted new series of Schiff base ligands (L1)-(L3) containing bidentate nitrogen atom. Their metal complexes were synthesized by coordinating the ligands with transition metals as Co(II), Cu(II), Ni(II) and Zn(II) and exhibited octahedral geometry. Their characterization was done with the help of spectral, physical and analytical analysis. Spectral and elemental analysis of all bidentate ligands and their corresponding 3d-metal chelates was consistent with their proposed structures, signifying the high purity of these compounds. For in-vitro studies, these metal complexes along their ligands were screened against the six bacterial strains; Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus and Streptococcus faecalis. Six fungal strains; Aspergillus niger, Trichophyton mentogrophytes, Epidermophyton floccosum, Trichophyton schoenleinii, Microscopum canis and Fusarium culmorum were used to study antifungal activity of the compounds. Bioactivity results exhibited that metal complexes showed higher antimicrobial potential as compared with their corresponding ligands. The enhanced activity resulted due to chelation that decreases the polarity of metal ions by complexing with bidentate ligands.

Phototriggered cytotoxic properties of tricarbonyl manganese(I) complexes bearing α-diimine ligands towards HepG2

Reaction between bromo tricarbonyl manganese(I) and N,N′-bis(phenyl)-1,4-diaza-1,3-butadiene ligands, bearing different electron-donating and electron-withdrawing groups R?=?OCH3, Cl, and NO2 in the ortho- and para-positions on the p

Design and application of diimine-based copper(i) complexes in photoredox catalysis

Structurally different bis(imino)copper(i) complexes were prepared in a highly modular manner and utilized as copper-based photocatalysts in the ATRA reactions of styrenes and alkyl halides. The new photocatalysts showed good catalytic activity and ensured efficient chemical transformations.

Synthesis, ir and nmr spectral correlations in some symmetrical diimines

A series of diimines have been synthesized by coupling of diamine with substituted benzaldehydes. The purities of these diimines were checked by their analytical and spectroscopic data. The spectral frequencies vCN (cm-1), NMR chemical shifts (v, ppm) of C-H and C=N of these diimines have been correlated with Hammett substituent constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral data has been studied.

Synthesis and characterization of novel organonickel and organocobalt complexes via carbonechlorine bond activation

The ortho-metalated nickel(II) complexes 3, 4, 7 and 8 were obtained by the reaction of ortho-halogeno aromatic bis-Schiff bases 1, 2, 5 and 6 with the stoichiometric amount of Ni(PM-3)4. The combination of 5 and 6 with two equivalents of Ni(PM-3)4 resulted in oxidative addition of the double CeCl bonds to afford ortho-bis-chelated nickel(II) complexes 9 and 10. The reaction of 6 with Co(PM-3)4 gave rise to dinuclear ortho-metalated cobalt(II) complex 12 through CeCl bond activation while the reaction of 5 with Co(PM-3)4 delivered bis-chelated cobalt(I) complex 11 through both CeCl and CeH bond activation. The structures of complexes 3, 4, 8, 9, 11 and 12 were determined by X-ray single crystal diffraction. The catalytic activity of bis-chelated cobalt(I) complex 11 as catalyst for C,C-coupling reaction was explored.

Copper-catalyzed amidation of aryl iodides in the presence of various chelating ligands

N,N′-Dibenzylethylenediamine is presented as a new, efficient, and versatile bidentate ligand suitable for the copper catalyzed formation of the C-N bond. This bidentate ligand has been demonstrated to facilitate the copper catalyzed cross-coupling reactions of aryl iodides with amides to afford the desired products in good to excellent yields.

Synthesis of a new dicompartment multifunctional groups ligand

Phenol-based acyclic ligand 1,6-bis(2-chlorobenzyl)-2,5-bis(2-hydroxy-3- formyl-5-methylbenzyl)-2,5-diazahexane, LH2 and its dilithium form Li2L possessing two dissimilar compartments having multi-functional groups were pre pared thr

Tetrahydroimidazoles - A promising group of expected NSAIDS - Their synthesis and anti-inflammatory activity

Several new 1, 2, 3-trisubstituted tetrahydroimidazoles (11-28) have been synthesised and their structures elucidated on the basis of spectral data. These compounds show promising anti-inflammatory activity by carrageenin induced paw edema test in rats and few of them showed an activity better than indomethacin.

Nickelacycles with anionic C-N-N′ terdentate ligands containing (5,5), (5,6), (5,7) and (6,5) membered fused rings. Reaction with ethylene

A series of nickelacycle complexes with di-Schiff bases acting as terdentate CNN- anionic ligands has been prepared. Oxidative addition of one C-X bond in mono- or di-ortho-halogenoaryl substituted ligands, N,N′-dibenzylidene-alkane-1,2-diamines (ethane, propane and butanediamines) and N,N′-bis(1,2-diphenylethylidene)ethane-1,2-diamine, to [Ni(cod)2] gives neutral complexes [NiX(CNN)] containing (5,5), (5,6), (5,7) and (6,5)-membered fused chelate rings (NiCN and NiNN respectively). Complexes from monohalogenoaryl substituted ligands are obtained as mixtures of two non-interchanging configurational isomers (E or Z stereochemistry about the non-metallated imine group). Cationic complexes [NiL(CNN)]BF4 are generated by halide abstraction from these neutral complexes by using TlBF4 and 2,4,6-Me3C5H2N or CH3CN as stabilizing ligand. In ionic compounds from monohalogenoaryl substituted ligands the formation of isomers by restricted rotation around the Cphenyl-Cmethinic bond is also observed. The 1H NMR spectra of complexes with (5,5), (5,6), (6,5) fused rings show fluxional behavior, the data being consistent with interconversion of two chelate ring conformations that are associated with the relative position of the non-metallated methinic moiety in the lower or the upper side of the coordination plane. Molecular structures of three ionic complexes [Ni(2,4,6-Me3C5H2N)(CNN)]BF4, were determined by X-ray single-crystal diffraction, revealing the effects of chelate sizes on the distortion of the coordination sphere around nickel. Ionic complexes [Ni(CH3CN)(CNN)]BF4 were tested as precursors of active species in the reaction with ethylene under pressure. The influence of the nickelacycle ring size on the insertion reaction is discussed, with moderate activities being observed only when the Ni-C bond is involved in a six-membered ring.

Synthesis of novel tetrahydroimidazole derivatives and studies for their biological properties

Ethylenediamine was reacted with suitable aromatic aldehydes in order to prepare their respective diSchiff bases. These compounds were then reduced to give the corresponding tetrahydrodiSchiff bases, which were low melting in nature. Finally, these derivatives were condensed with different aromatic aldehydes to give the desired tetrahydroimidazoles. The structures of all these compounds were established on the basis of spectral data. These novel tetrahydroimidazoles showed promising anti-inflammatory and analgesic activity. The compounds were also screened for their anti-bacterial property against Staphylococcus aureus and Escherichia coli.