815600-95-4

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 459-23-4 4-fluorobenzaldoxime 
• 52-90-4 L-Cysteine 
• 1194-02-1 4-fluorobenzonitrile 
• 815600-94-3 methyl 2-(4-fluorophenyl)-4,5-dihydrothiazole-4-carboxylate 

Downstream Products

• 1314419-46-9 methyl 2-(4-fluorophenyl)thiazole-4-carboxylate 
• 1370731-42-2 methyl 2-(p-fluorophenyl)-5-phenylthiazole-4-carboxylate 
• 815600-94-3 methyl 2-(4-fluorophenyl)-4,5-dihydrothiazole-4-carboxylate 

Relevant academic research and scientific papers

Pd(ii)-catalyzed direct C5-arylation of azole-4-carboxylates through double C-H bond cleavage

The first palladium-catalyzed direct C5-arylation of azole-4-carboxylates with simple unactivated arenes through double C-H bond cleavage is realized. This protocol provided a straightforward access to diverse 5-arylsubstituted azole-4-carboxylic derivatives with good functional group tolerance. The Royal Society of Chemistry 2012.

THIAZOLINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)

The present invention is directed to novel thiazoline derivatives of the general fomula (I); wherein all variables are as herein defined, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by t