816448-91-6Relevant academic research and scientific papers
Regioselective direct oxidative C-H cyanation of quinoline and its derivatives catalyzed by vanadium-containing heteropoly acids
Yamaguchi, Kazuya,Xu, Ning,Jin, Xiongjie,Suzuki, Kosuke,Mizuno, Noritaka
supporting information, p. 10034 - 10037 (2015/06/22)
A direct oxidative C-H cyanation of quinoline and its derivatives using trimethylsilyl cyanide as the cyano source and molecular oxygen as the terminal oxidant has been developed. In the presence of catalytic amounts of vanadium-containing heteropoly acids, e.g., H7PV4Mo8O40, cyanation of various quinoline and its derivatives preferentially took place at the 4-position, affording the corresponding substituted 4-cyanoquinolines as the major products.
QUINOLYL AMIDE DERIVATIVES AS CCR-5 ANTAGONISTS
-
Page 30; 31, (2010/02/10)
The present invention relates to a series of compounds which are CCR-5 receptor antagonists of the general formula (I): or a pharmaceutically acceptable salt thereof, wherein the variables are defined herein.
