816448-92-7

Basic information

• Product Name: 4-[(E)-(4-bromophenyl)(ethoxyimino)methyl]-1-(4-methyl-4-piperidinyl)piperidine
• Synonyms: 4-[(E)-(4-bromophenyl)(ethoxyimino)methyl]-1-(4-methyl-4-piperidinyl)piperidine
• CAS NO: 816448-92-7
• Molecular Weight: 408.382
• Mol File: 816448-92-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[(E)-(4-bromophenyl)(ethoxyimino)methyl]-1-(4-methyl-4-piperidinyl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(E)-(4-bromophenyl)(ethoxyimino)methyl]-1-(4-methyl-4-piperidinyl)piperidine(816448-92-7)
• EPA Substance Registry System: 4-[(E)-(4-bromophenyl)(ethoxyimino)methyl]-1-(4-methyl-4-piperidinyl)piperidine(816448-92-7)

Safety Data

• Hazardous Substances Data: 816448-92-7(Hazardous Substances Data)

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 305794-42-7 4-[2-(4-bromophenyl)-1,3-dioxolan-2-yl]-1'-(tert-butoxycarbonyl)-4'-cyano-1,4'-bipiperidine 
• 305794-43-8 4-[2-(4-bromophenyl)-1,3-dioxolan-2-yl]-1'-(tert-butoxycarbonyl)-4'-methyl-1,4'-bipiperidine 
• 305794-45-0 4-(4-bromobenzoyl)-1'-(tert-butoxycarbonyl)-4'-methyl-1,4'-bipiperidine 
• 305794-44-9 (4-bromo-phenyl)-(4'-methyl-[1,4']bipiperidinyl-4-yl)-methanone 
• 203186-01-0 1-[4-(4-bromobenzoyl)piperidin-1-yl]-2,2,2-trifluoroethanone 
• 203186-02-1 4-[2-(4-bromophenyl)-1,3-dioxolan-2-yl]-piperidine 
• 126501-71-1 1-(2,2,2-trifluoroacetyl)piperidine-4-carbonyl chloride 
• 126501-70-0 1-(2,2,2-trifluoroacetyl)piperidine-4-carboxylic acid 
• 498-94-2 isonipecotic acid 
• 438207-92-2 4-[(4-bromo-phenyl)-ethoxyimino-methyl]-4'-methyl-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis, SAR, and biological evaluation of oximino-piperidino-piperidine amides. 1. Orally bioavailable CCR5 receptor antagonists with potent anti-HIV activity

We previously reported the discovery of 4-[(Z)-(4-bromophenyl)(ethoxyimino)methyl]-1′-[(2,4-dimethyl-3 -pyridinyl)carbonyl]-4′-methyl-1,4′-bipipefidine N-oxide 1 (SCH 351125) as an orally bioavailable human CCR5 antagonist for the treatment of HIV-1 infec