81654-64-0

Basic information

• Product Name: N-(4-cyanophenyl)-2-iodobenzamide
• Synonyms: N-(4-cyanophenyl)-2-iodobenzamide
• CAS NO: 81654-64-0
• Molecular Formula: C₁₄H₉IN₂O
• Molecular Weight: 348.13853
• Mol File: 81654-64-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-cyanophenyl)-2-iodobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-cyanophenyl)-2-iodobenzamide(81654-64-0)
• EPA Substance Registry System: N-(4-cyanophenyl)-2-iodobenzamide(81654-64-0)

Safety Data

• Hazardous Substances Data: 81654-64-0(Hazardous Substances Data)

Upstream product

• 18523-41-6 4-azidobenzonitrile 
• 88-67-5 2-Iodobenzoic acid 
• 609-67-6 2-Iodobenzoyl chloride 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 40101-61-9 nitrile of N-phthaloyl-4-aminobenzoic acid 
• 95202-40-7 4-[4-oxoquinazolin-3(4H)-yl]benzonitrile 

Relevant articles and documents

Traceless selenocarboxylates for the one-pot synthesis of amides and derivatives

We have recently reported a one-pot procedure for glycosyl amides synthesis using selenocarboxylate as traceless reagent. Herein, we present a further application of selenocarboxylate-azide reaction for amide bond formation on a broader range of substrates, including heterocyclic systems and fatty acid. This method proved to be highly efficient for the synthesis of primary and secondary amides, sulfonamides, imides, phosphoramide and also carbamate.

Palladium-catalyzed intramolecular C-H arylation of 2-halo-: N -Boc- N -arylbenzamides for the synthesis of N-H phenanthridinones

A palladium catalyzed synthesis of N-H phenanthridinones was developed via C-H arylation. The protocol gives phenanthridinones regioselectively by one-pot reaction without deprotection. It exhibits broad substrate scope and affords targets in up to 95% yields. Importantly, it could be applied for the less reactive o-chlorobenzamides.