81668-74-8

Basic information

• Product Name: Carbonic acid 2-(4-chloro-benzenesulfonyl)-ethyl ester (2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester
• Synonyms: Carbonic acid 2-(4-chloro-benzenesulfonyl)-ethyl ester (2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester
• CAS NO: 81668-74-8
• Molecular Weight: 488.903
• Mol File: 81668-74-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbonic acid 2-(4-chloro-benzenesulfonyl)-ethyl ester (2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbonic acid 2-(4-chloro-benzenesulfonyl)-ethyl ester (2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester(81668-74-8)
• EPA Substance Registry System: Carbonic acid 2-(4-chloro-benzenesulfonyl)-ethyl ester (2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester(81668-74-8)

Safety Data

• Hazardous Substances Data: 81668-74-8(Hazardous Substances Data)

Upstream product

• 112723-64-5 2-(p-chlorophenylsulfonyl)ethyl chloroformate 
• 50-89-5 thymidine 

Downstream Products

• 5535-51-3 p-chlorophenyl vinyl sulfone 
• 50-89-5 thymidine 

Relevant articles and documents

THE APPLICATION OF 2-(4-CHLOROPHENYL)-SULFONYLETHOXYCARBONYL (CPSEC) GROUP IN THE SYNTHESIS OF A DNA SEGMENT USING THE PHOSPHOTRIESTER APPROACH

The new base labile CPSEC group has been successfully employed for the protection of the 5'-hydroxyl function to synthesize a "universal Stop codon" DNA sequence: 5'd(TCAATCAATCA)3'.