81674-79-5 Usage
Uses
Used in Pharmaceutical Industry:
Guaimesal is used as an aspirin prodrug for its potential to provide the same therapeutic effects as aspirin. It is a degradation product of acetylsalicylic acid, which means it can be metabolized into aspirin in the body, offering the same benefits as aspirin, such as pain relief, fever reduction, and anti-inflammatory effects.
Additionally, Guaimesal may have potential applications in other industries, such as cosmetics or food and beverages, due to its similar properties to aspirin. However, more research and development would be needed to explore these potential applications further.
Check Digit Verification of cas no
The CAS Registry Mumber 81674-79-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,6,7 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 81674-79:
(7*8)+(6*1)+(5*6)+(4*7)+(3*4)+(2*7)+(1*9)=155
155 % 10 = 5
So 81674-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H14O5/c1-16(20-14-10-6-5-9-13(14)18-2)19-12-8-4-3-7-11(12)15(17)21-16/h3-10H,1-2H3
81674-79-5Relevant academic research and scientific papers
Enzymatic and nonenzymatic in vitro hydrolysis of 2-methyl-2-[2-(methoxy)phenoxy]-4H-1,3-benzodioxin-4-one and 2-methoxyphenyl O-acetylsalicylate
Hundewadt,Senning
, p. 545 - 547 (2007/10/02)
This paper is concerned with the synthesis and physical properties as well as the enzymatic and nonenzymatic in vitro hydrolysis of the potential aspirin prodrug MR 693 (5) and the salicylic acid prodrug guacetisalum (6). The half-lives of both prodrugs and the amount of aspirin regenerated in each hydrolytic run for 5 have been estimated over a wide range of pH values.
Aspirin Prodrugs: 2-Methyl-2-aryloxy-4H-1,3-benzodioxin-4-ones Acting as True Aspirin Prodrugs
Hundewadt, Marianne,Senning, Alexander
, p. 746 - 751 (2007/10/02)
This paper is concerned with the synthesis, physical properties and both non-enzymatic and enzymatic in vitro hydrolysis of the title compounds 5.Ten new and two known compounds 5 have been synthesized and characterized.In vitro enzymatic and non-enzymatic hydrolysis of ten compounds 5, including the two known, revealed several of them to behave as true aspirin prodrugs.
