817167-06-9

Upstream product

• 91229-97-9 (S)-2-[N-(tert-butoxycarbonyl)amino]-5-hydroxypentanoic acid benzyl ester 
• 78658-49-8 Boc-Glu(OSu)-OBn 
• 30924-93-7 Boc-Glu-OBn 
• 817167-04-7 C₃₁H₅₁NO₇Si 
• 817166-95-3 [(1S)-1-[(4R)-4-benzyl-5-oxotetrahydrofuran-(2R)-2-yl]-4-(tert-butyldimethylsilanyloxy)butyl]carbamic acid tert-butyl ester 
• 817166-99-7 (4R,5S)-5-tert-butoxycarbonylamino-8-(tert-butyldimethylsilanyloxy)-4-hydroxyoctanoic acid methyl ester 
• 471282-37-8 [3-tert-butoxycarbonylamino-6-(tert-butyldimethylsilanyloxy)-2-oxohexyl]phosphonic acid dimethyl ester 
• 817166-98-6 (2S)-2-tert-butoxycarbonylamino-5-(tert-butyldimethyl-silanyloxy)-pentanoic acid benzyl ester 
• 817166-97-5 5-tert-butoxycarbonylamino-8-(tert-butyldimethylsilanyloxy)-4-oxooctanoic acid methyl ester 
• 817166-96-4 [4-(tert-butyldimethylsilanyloxy)-(1S)-1-(5-oxotetrahydrofuran-(2R)-2-yl)butyl]carbamic acid tert-butyl ester 
• 817167-05-8 (4S)-4-[(4R)-4-benzyl-5-oxotetrahydrofuran-(2R)-2-yl]-4-[bis(tert-butoxycarbonyl)amino]butyric acid 
• 146548-59-6 2,4,6-trimethoxy benzyl amine hydrochloride 

Downstream Products

• 817166-93-1 (2R,4R,5S)-2-benzyl-5-tert-butoxycarbonylamino-4-(tert-butyldimethylsilanyloxy)-7-(2,4,6-trimethoxybenzylcarbamoyl)heptanoic acid 
• 817167-07-0 [(1S)-1-[(4R)-4-benzyl-5-oxotetrahydrofuran-(2R)-2-yl]-3-(2,4,6-trimethoxybenzylcarbamoyl)propyl]carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of a Gln-Phe hydroxy-ethylene dipeptide isostere

(Chemical Equation Presented) The protected Gln-Phe hydroxyethylene dipeptide isostere 1 was synthesized as a precursor for preparation of potential inhibitors of Botulinum neurotoxin B metalloprotease. The method allows for the synthesis of additional hydroxyethylene dipeptide isosteres such as 2 with functionalized P1 side chains. The isosteres prepared were coupled with a dipeptide to produce protected pseudotetrapeptide derivatives.