Cas 81731-51-3,1-(2-hydroxyethyl)-4-(2,3,4-trimethoxybenzyl)piperazine

81731-51-3

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Basic information

Product Name: 1-(2-hydroxyethyl)-4-(2,3,4-trimethoxybenzyl)piperazine
Synonyms: 1-(2-hydroxyethyl)-4-(2,3,4-trimethoxybenzyl)piperazine
CAS NO:81731-51-3
Molecular Formula:
Molecular Weight: 310.393
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-(2-hydroxyethyl)-4-(2,3,4-trimethoxybenzyl)piperazine(CAS DataBase Reference)
NIST Chemistry Reference: 1-(2-hydroxyethyl)-4-(2,3,4-trimethoxybenzyl)piperazine(81731-51-3)
EPA Substance Registry System: 1-(2-hydroxyethyl)-4-(2,3,4-trimethoxybenzyl)piperazine(81731-51-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 81731-51-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 81731-51-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,3 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 81731-51:
(7*8)+(6*1)+(5*7)+(4*3)+(3*1)+(2*5)+(1*1)=123
123 % 10 = 3
So 81731-51-3 is a valid CAS Registry Number.

81731-51-3Upstream product

81731-51-3Downstream Products

81731-51-3Relevant academic research and scientific papers

METHODS OF SYNTHESIZING 2-[4-[(2,3,4-TRIMETHOXYPHENYL)METHYL]PIPERAZIN-1-YL]ETHYL PYRIDINE-3-CARBOXYLATE

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Paragraph 0050-0051, (2022/01/04)

The invention provides methods of chemical synthesis of the pharmacological agent 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate, also called CV-8972. The methods entail formation of a free base form of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethanol, also called CV-8814, as intermediate without producing a salt form of CV-8814.

METHODS OF TREATING CANCER USING TRIMETAZIDINE-BASED COMPOUNDS

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Page/Page column 83, (2020/10/09)

The invention provides compositions and method for treating a subject having cancer.

METHODS OF ALTERING CARDIAC REMODELING USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION

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Page/Page column 70, (2020/12/11)

The invention provides methods for altering cardiac remodeling in a subject by providing a compound that shifts cellular metabolism from fatty acid oxidation to glucose oxidation.

COMBINATION THERAPIES THAT INCLUDE AN AGENT THAT PROMOTES GLUCOSE OXIDATION AND AN INHIBITOR OF PYRUVATE DEHYDROGENASE KINASE

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Page/Page column 70, (2020/12/29)

The invention provides combination therapies that include an agent that shifts cellular metabolism from fatty acid oxidation to glucose oxidation and an inhibitor of pyruvate dehydrogenase kinase. The combination therapies are useful for treating a variet

INHIBITORS OF CPT IN THE CENTRAL NERVOUS SYSTEM AS ANTIDIABETIC AND/OR ANTI-OBESITY DRUGS

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Page/Page column 12-13, (2010/11/28)

The invention relates to a new class of compounds with inhibitory action on carnitine palmitoyl transferase (CPT) in the central nervous system (SNC), derived from trimetazidine and perhexiline, preferentially selective for the hepatic form of CPT1 (CPT1L

Synthesis and antimalarial evaluation of a series of piperazinyl flavones

Auffret, Gwenola,Labaied, Mehdi,Frappier, Francois,Rasoanaivo, Philippe,Grellier, Philippe,Lewin, Guy

, p. 959 - 963 (2007/10/03)

A series of 27 flavonoid derivatives containing a piperazinyl chain have been synthesized and tested for their antiplasmodial activity. Diverse substitution patterns on piperazinyl and flavone moieties were examined and found to affect the activity differ

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