81777-54-0Relevant academic research and scientific papers
Nucleic acid related compounds. 38. Smooth and high-yield iodination and chlorination at C-5 of uracil bases and p-toluyl-protected nucleosides
Robins, Morris, J.,Barr, Philip J.,Giziewicz, Jerzy
, p. 554 - 557 (1982)
Treatment of uracil bases and protected nucleosides with iodine monochloride (ICl) gave the corresponding 5-iodouracil products in over 95percent purified yields.Analogously facile chlorination was effected with iodobenzene dichloride (PhICl2).Protection of the nucleosides as p-toluyl esters provided reactants that were soluble in organic solvents and crystallized readily in high yields.
Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
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, (2008/06/13)
Use of a compound of the formula STR1 wherein A is β-2''-deoxy-D-ribofuranosyl or β-D-arabinofuranosyl;R 1 is hydroxy or amino;R 2 is cycloalkyl or alkyl-substituted cycloalkyl containing 1-5 carbon atoms; saturated or unsaturated, straight or branched al
