81797-27-5 Usage
General Description
This complex chemical compound, also known as (+)-Catharanthine, is derived from the plant Catharanthus roseus and belongs to the class of alkaloids. It has a tetrahydroindole core structure and is classified as an indole alkaloid. The chemical features a 5aβ,13aα,14,14a-tetrahydroindolo[3',2':4,5]pyrrolo[2,1-c][1,4]benzodiazepine-7,13(5H,12H)-dione backbone, and its stereochemistry includes a 5aR configuration and a 14aβ-(1,1-dimethyl-2-propenyl) substituent. [5aR,(+)]-14aβ-(1,1-Dimethyl-2-propenyl)-5aβ,13aα,14,14a-tetrahydroindolo[3',2':4,5]pyrrolo[2,1-c][1,4]benzodiazepine-7,13(5H,12H)-dione has potential pharmacological applications due to its diverse biological activities, but it requires further research for a comprehensive understanding of its medicinal properties.
Check Digit Verification of cas no
The CAS Registry Mumber 81797-27-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,9 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 81797-27:
(7*8)+(6*1)+(5*7)+(4*9)+(3*7)+(2*2)+(1*7)=165
165 % 10 = 5
So 81797-27-5 is a valid CAS Registry Number.
81797-27-5Relevant articles and documents
Stereospecific synthesis of aszonalenins by using two recombinant prenyltransferases
Yin, Wen-Bing,Cheng, Jun,Li, Shu-Ming
, p. 2202 - 2207 (2009)
In previous studies, two prenyltransferases were overproduced and characterised biochemically. AnaPT from Neosartorya fischeri is involved in the biosynthesis of acetylaszonalenin and was shown to catalyse the C3-prenylation of (R)-benzodiazepinedione (6)
The biosynthesis of the mould metabolites roquefortine and aszonalenin from L-[2,4,5,6,7-2H5]tryptophan
Bhat,Harrison,Lamont
, p. 10663 - 10668 (2007/10/02)
L-[2,4,5,6,7-2H5]Tryptophan was incorporated into roquefortine 2 by Penicillium roqueforti and aszonalenin 3 by Aspergillus zonatus with retention in each case of five deuterium atoms; the 5a-hydrogen of both metabolites is derived from the 2-hydrogen of tryptophan.
