81805-53-0

Basic information

• Product Name: Benzenemethanol, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-
• CAS NO: 81805-53-0
• Molecular Formula: C14H24O2Si
• Molecular Weight: 252.429
• Mol File: 81805-53-0.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(81805-53-0)
• EPA Substance Registry System: Benzenemethanol, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(81805-53-0)

Safety Data

• Hazardous Substances Data: 81805-53-0(Hazardous Substances Data)

Usage

General Description

Benzenemethanol, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]- is a chemical compound with a complex structure. It contains a benzene ring attached to a methanol group, as well as a tert-butyl and dimethylsilyl groups connected to an oxygen atom. Benzenemethanol, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]- is often used in the synthesis of organic compounds and as a reagent in various chemical reactions. It may also have applications in the field of pharmaceuticals or as a building block for more complex molecules. Overall, this chemical has potential uses in a variety of industries and research fields due to its unique structure and properties.

Upstream product

• 288-32-4 1H-imidazole 
• 626-18-6 1,3-dimethanol benzene 
• 18173-64-3 tert-butyldimethylsilanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1026659-81-3 tert-Butyl-(3-iodomethyl-benzyloxy)-dimethyl-silane 
• 478190-05-5 ((3-(bromomethyl)benzyl)oxy)(tert-butyl)dimethylsilane 
• 81168-11-8 3-(((tert-butyldimethylsilyl)oxy)methyl)benzaldehyde 
• 213620-92-9 (Z)-7-[3-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-7-pyridin-3-yl-hept-6-enoic acid methyl ester 
• 213620-90-7 (E)-7-[3-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-7-pyridin-3-yl-hept-6-enoic acid methyl ester 
• 160694-15-5 [3-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-pyridin-3-yl-methanone 
• 125604-06-0 1-(3-(hydroxymethyl)phenyl)ethan-1-one 
• 1003838-62-7 1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)ethanone 

Relevant articles and documents

Diverted Total Synthesis of Carolacton-Inspired Analogs Yields Three Distinct Phenotypes in Streptococcus mutans Biofilms

The oral microbiome is a dynamic environment inhabited by both commensals and pathogens. Among these is Streptococcus mutans, the causative agent of dental caries, the most prevalent childhood disease. Carolacton has remarkably specific activity against S. mutans, causing acid-mediated cell death during biofilm formation; however, its complex structure limits its utility. Herein, we report the diverted total synthesis and biological evaluation of a rationally designed library of simplified analogs that unveiled three unique biofilm phenotypes further validating the role of natural product synthesis in the discovery of new biological phenomena.

EP4 antagonists number

We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.

A Chemical Disruptor of the ClpX Chaperone Complex Attenuates the Virulence of Multidrug-Resistant Staphylococcus aureus

The Staphylococcus aureus ClpXP protease is an important regulator of cell homeostasis and virulence. We utilized a high-throughput screen against the ClpXP complex and identified a specific inhibitor of the ClpX chaperone that disrupts its oligomeric sta