81807-56-9Relevant academic research and scientific papers
A NEW METHOD FOR THE SYNTHESIS OF β-HYDROXYESTERS BY USING METALLIC TIN
Harada, Taira,Mukaiyama, Teruaki
, p. 161 - 164 (1982)
Metallic tin or activated metallic tin, prepared by reduction of stannous chloride with lithium aluminum hydride, smoothly reacts with α-haloesters to yield tin enolates, which in turn react with carbonyl compounds under mild conditions to give, after hydrolysis, β-hydroxyesters in high yields.
