81835-79-2

Upstream product

• 421-20-5 Methyl fluorosulfonate 
• 81835-68-9 3,3-ethylenedioxy-N-(2,3,4-trimethoxybenzylidene)pentylamine 
• 109463-90-3 1-benzyl(methyl)aminopentan-3-one hydrochloride 
• 109463-91-4 1-methylaminopentan-3-one hydrochloride 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 
• 81835-71-4 trans-3-methyl-2-(2,3,4-trimethoxyphenyl)-4-piperidone ethylene acetal 
• 81835-64-5 1-phthalimido-3-pentanone ethylene acetal 
• 81835-62-3 1-phthalimido-3-pentanone 
• 81835-66-7 1-amino-3-pentanone ethylene acetal 
• 32830-97-0 1-chloro-3-pentanone 
• 81835-74-7 trans-3-methyl-2-(2,3,4-trimethoxyphenyl)-4-piperidone 
• 74-88-4 methyl iodide 
• 81835-77-0 trans-1,3-dimethyl-2-(2,3,4-trimethoxyphenyl)-4-piperidone ethylene acetal 

Downstream Products

• 109463-97-0 (2r,3t,4t)-1,3-dimethyl-2-(2,3,4-trimethoxyphenyl)piperidine-4-carbonitrile 
• 109463-97-0 (2r,3t,4c)-1,3-dimethyl-2-(2,3,4-trimethoxyphenyl)piperidine-4-carbonitrile 

Relevant academic research and scientific papers

Benzomorphan-related Compounds. Part 21. Synthesis of 7,8-Benzomorphans via 2-Aryl-4-piperidones

A new synthesis of 1,2,3,4,5,6-hexahydro-1,5-methano-2-benzazocines (7,8-benzomorphans) based on the acid-catalysed cyclization of 2-arylpiperidine-4-carboxylic acids is reported.The required carboxylic acids were prepared from 2-aryl-4-piperidones, by re

A Novel Synthesis of 2-Aryl-4-Piperidones By Mannich Cyclization of Iminoketals (1)

2-Aryl-4-piperidones have been synthesized by condensation between an aromatic aldehyde and a β-aminoketone ethylene ketal, and further cyclization of the resulting iminoketal with dry hydrogen chloride or anhydrous p-toluenesulfonic acid.Alternatively, r

MANNICH CYCLIZATION INVOLVING THE α-POSITION OF KETALS: SYNTHESIS OF 2-ARYL-4-PIPERIDONES AND 2-ARYL-3-ACYLPYRROLIDINES

A new method for the preparation of 2-aryl-4-piperidones and 2-aryl-3-acylpyrrolidines based on the acid-induced intramolecular cyclization between an iminium salt and the α-position of a ketal group is reported.