81932-04-9

Usage

Uses

Used in Pharmaceutical Industry:
4-(Bromodifluoromethoxy)nitrobenzene serves as an intermediate in the synthesis of various pharmaceuticals. Its unique structural features, including the bromine and fluorine atoms, contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Production:
4-(BROMODIFLUOROMETHOXY)NITROBENZENE is utilized in the production of agrochemicals, where it exhibits pesticidal and herbicidal properties. Its application helps in controlling pests and weeds, thereby enhancing crop protection and yield.
Used as a Building Block for Organic Compounds:
4-(Bromodifluoromethoxy)nitrobenzene is employed as an intermediate for the manufacture of other organic compounds. Its versatility in chemical reactions allows for the creation of a wide range of products with diverse applications.
Used in Chemical Research:
Due to its unique structure and reactivity, 4-(Bromodifluoromethoxy)nitrobenzene is also used in chemical research to explore new reaction pathways and develop innovative synthetic methods.
It is crucial to handle 4-(Bromodifluoromethoxy)nitrobenzene with care, considering its potential health hazards and environmental impact. Proper safety measures should be implemented during its production, use, and disposal to minimize any adverse effects.

Upstream product

• 353-59-3 halon-1211 
• 1124-31-8 potassium 4-nitrophenolate 
• 75-61-6 dibromodifluoromethane 
• 100-02-7 4-nitro-phenol 
• 75-62-7 Bromotrichloromethane 
• 383670-74-4 ethyl 2,2-difluoro-2-(4-nitrophenoxy)acetate 
• 24210-51-3 2,2-difluoro-2-(4-nitrophenoxy)acetic acid 

Relevant academic research and scientific papers

18F-Labeling of Aryl-SCF3, -OCF3 and -OCHF2 with [18F]Fluoride

We report that halogenophilic silver(I) triflate permits halogen exchange (halex) nucleophilic 18F-fluorination of aryl-OCHFCl, -OCF2Br and -SCF2Br precursors under mild conditions. This AgI-mediated process allows for the first time access to a range of 18F-labeled aryl-OCHF2, -OCF3 and -SCF3 derivatives, inclusive of [18F]riluzole. The 18F-labeling of these medicinally important motifs expands the radiochemical space available for PET applications. A halogen exchange (halex) 18F-fluorination process offers access for the first time to 18F-labeled arylOCF3, arylOCHF2 and arylSCF3, three motifs of established medicinal importance in PET radiotracers. The use of silver(I) triflate is critical to permit 18F-labeling under mild conditions.

Insecticidal 3-difluoromethoxyphenyl-1-phenylcarbamoyl-2-pyrazolines

Pyrazoline derivatives useful as insecticides having the formula STR1 wherein R1 represents hydrogen atom, a lower alkyl group, (CH2)n CN group, (CH2)n OR group, phenyl group or a halogen-substituted phenyl group; R2 represents hydrogen atom or methyl group; Y represents hydrogen atom or chlorine atom; X represents oxygen atom, sulfur atom, sulfinyl or sulfonyl group; R3 represents a halogen-substituted lower alkyl group; and n is integer 1 to 3 and R represents a lower alkyl group.

SYNTHESE DE COMPOSES AROMATIQUES COMPORTANT LES GROUPEMENTS OCF2Br ET SCF2Br-II; ACTION DE CF2Br2 ET DE CF2BrCl SUR DES THIOPHENATES ET PHENATES DE POTASSIUM DIVERSEMENT SUBSTITUES

The reaction of dibromodifluoromethane and bromochlorodifluoromethane with substituted potassium thiophenoxides and phenoxides leads to the formation of new aromatic compounds bearing OCF2Br and SCF2Br groups.