81950-36-9

Basic information

• Product Name: [4-(7-Ethoxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-phenyl]-acetic acid
• Synonyms: [4-(7-Ethoxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-phenyl]-acetic acid
• CAS NO: 81950-36-9
• Molecular Weight: 352.414
• Mol File: 81950-36-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4-(7-Ethoxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-phenyl]-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(7-Ethoxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-phenyl]-acetic acid(81950-36-9)
• EPA Substance Registry System: [4-(7-Ethoxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-phenyl]-acetic acid(81950-36-9)

Safety Data

• Hazardous Substances Data: 81950-36-9(Hazardous Substances Data)

Upstream product

• 81950-40-5 [4-(7-Ethoxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-phenyl]-acetic acid ethyl ester 
• 55453-49-1 ethyl 4-(ω-bromoacetyl)phenylacetate 
• 1528-42-3 ethyl 4-acetylphenylacetate 
• 94-45-1 2-Amino-6-ethoxybenzothiazole 

Relevant articles and documents

Synthesis and Anthiinflammatory Activity of Some Arylimidazothiazolyl- and Arylimidazobenzothiazolyl-acetic Acids

Three series of the title compounds, imidazothiazolyl-, imidazobenzothiazolyl- and imidazobenzothiazolylaryl-acetic acids (II,III and IV) have been synthesised for evaluation as potential anti-inflammatory agents.Compounds II have been synthesised by condensing ethyl (2-amino-4-aryl-5-thiazolyl)acetate (VI) with phenacyl bromides followed by hydrolysis of the resultant esters (VII).III are obtained by the condensatiion of ethyl 2-aminobenzothiazole-6-acetate with phenacyl bromides followed by hydrolysis of the resultant esters (IX).Compound IV result from the treatment of 2-aminobenzothiazoles with ethyl 4(ω-bromoacetylphenyl)acetate (XI) followed by hydrolysis of the esters (XII).Some of the title compounds show good antiinflammatory activity.